ITGB8 and RAPGEF5

ITGB8

RAPGEF5

Description integrin subunit beta 8 Rap guanine nucleotide exchange factor 5
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Allergic rhinitis ( 31361310)
  • Asthma ( 31361310 31959851 30929738 34103634 31619474)
  • Asthma (childhood onset) ( 30929738)
  • Asthma onset (childhood vs adult) ( 30929738)
  • Asthma or allergic disease (pleiotropy) ( 29785011)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Body shape index ( 34021172)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Eosinophil counts ( 29403010 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • Hip circumference adjusted for BMI ( 34021172)
  • Inflammatory bowel disease ( 28067908)
  • Medication use (adrenergics, inhalants) ( 31015401)
  • Metabolite levels ( 23823483)
  • Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
  • Prostate cancer ( 29892016)
  • Type 1 diabetes ( 34012112)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 11 interacting genes: CHN2 HOXA1 ITGAV PSPH RAPGEF5 RRAGD SH2D3A SP4 TGFB1 TOMM7 VTN 8 interacting genes: ITGB8 MRAS PLAC9 RAP1A RAP2A RAP2B TMEM253 VANGL1
Entrez ID 3696 9771
HPRD ID 05001 15208
Ensembl ID ENSG00000105855 ENSG00000136237
Uniprot IDs P26012 Q9BUG9 A8MQ07 Q5JPD2 Q92565
PDB IDs 6DJP 6OM1 6OM2 6UJA 6UJB 6UJC 1WGY
Enriched GO Terms of Interacting Partners?
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