ITGB8 and SP4

ITGB8

SP4

Description integrin subunit beta 8 Sp4 transcription factor
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Allergic rhinitis ( 31361310)
  • Asthma ( 31361310 31959851 30929738 34103634 31619474)
  • Asthma (childhood onset) ( 30929738)
  • Asthma onset (childhood vs adult) ( 30929738)
  • Asthma or allergic disease (pleiotropy) ( 29785011)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Body shape index ( 34021172)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Eosinophil counts ( 29403010 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • Hip circumference adjusted for BMI ( 34021172)
  • Inflammatory bowel disease ( 28067908)
  • Medication use (adrenergics, inhalants) ( 31015401)
  • Metabolite levels ( 23823483)
  • Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
  • Prostate cancer ( 29892016)
  • Type 1 diabetes ( 34012112)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • Acute lymphoblastic leukemia (childhood) ( 29348612)
  • Age at first sexual intercourse ( 34211149)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Apolipoprotein B levels ( 32203549)
  • Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
  • Bipolar disorder ( 31043756)
  • General cognitive ability ( 29844566)
  • LDL cholesterol levels ( 32203549)
  • Major depressive disorder ( 20125088)
  • Major depressive disorder (broad) ( 20038947)
  • Multiple cancers (lung cancer, gastric cancer, and squamous cell carcinoma) ( 23103227)
  • Multisite chronic pain ( 33830993 31194737)
  • Plateletcrit ( 32888494)
  • Schizophrenia ( 30285260)
  • Temporomandibular joint disorder ( 28081371)
Interacting Genes 11 interacting genes: CHN2 HOXA1 ITGAV PSPH RAPGEF5 RRAGD SH2D3A SP4 TGFB1 TOMM7 VTN 35 interacting genes: ADAM15 AP1M1 ATXN7L1 BANP CIB3 COL8A1 E2F1 ELK3 FOXP2 GTF2A1 HIVEP1 HYPK ITGB8 LMO3 LNX1 MCRS1 NFYC NKX3-1 NRF1 PELI2 PNKP POGZ POU2F1 PRR20A PRR20B PRR20C PRR20D PRR20E PRSS59P SERF2 SP1 SPANXN2 SPANXN3 VEZF1 ZBTB7A
Entrez ID 3696 6671
HPRD ID 05001 02764
Ensembl ID ENSG00000105855 ENSG00000105866
Uniprot IDs P26012 Q9BUG9 A0A3B3IRW4 Q02446 Q32M51
PDB IDs 6DJP 6OM1 6OM2 6UJA 6UJB 6UJC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?