IDO1 and DCTN6

		IDO1	DCTN6
Description		indoleamine 2,3-dioxygenase 1	dynactin subunit 6
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Kinetochore Centrosome Cytosol Dynactin Complex
	Molecular Function	Tryptophan 2,3-dioxygenase Activity Electron Transfer Activity Heme Binding Indoleamine 2,3-dioxygenase Activity Metal Ion Binding	Dynein Complex Binding
	Biological Process	Immune System Process Tryptophan Catabolic Process Female Pregnancy Tryptophan Catabolic Process To Kynurenine Electron Transport Chain 'de Novo' NAD Biosynthetic Process From Tryptophan Regulation Of Activated T Cell Proliferation Positive Regulation Of T Cell Apoptotic Process	Mitotic Spindle Organization
Pathways		Tryptophan catabolism	MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Drugs		Nitric Oxide Cannabidiol Medical Cannabis Nabiximols
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood protein levels ( 29875488)	Breast size ( 27182965) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		11 interacting genes: ADRB3 APP DCTN6 DDX24 DUSP4 FBXL17 PPP1R16A RBPMS SFRP1 SLC20A2 TERF2IP	9 interacting genes: APP CDK1 ERRFI1 HSPB2 IDO1 NCOA3 PMEPA1 RPSA UBXN8
Entrez ID		3620	10671
HPRD ID		00935	09907
Ensembl ID		ENSG00000131203	ENSG00000104671
Uniprot IDs		A0A348GSI3 P14902	O00399
PDB IDs		2D0T 2D0U 4PK5 4PK6 4U72 4U74 5EK2 5EK3 5EK4 5ETW 5WHR 5WMU 5WMV 5WMW 5WMX 5WN8 5XE1 6AZU 6AZV 6AZW 6CXU 6CXV 6DPQ 6DPR 6E35 6E40 6E41 6E42 6E43 6E44 6E45 6E46 6F0A 6KOF 6KPS 6KW7 6MQ6 6O3I 6PU7 6PZ1 6R63 6UBP 6V52 6WJY 7A62 7AH4 7AH5 7AH6	3TV0
Enriched GO Terms of Interacting Partners?
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