DCTN6 and UBXN8

		DCTN6	UBXN8
Description		dynactin subunit 6	UBX domain protein 8
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Centrosome Cytosol Dynactin Complex	Ubiquitin Ligase Complex Nucleoplasm Nucleolus Endoplasmic Reticulum Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Dynein Complex Binding	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Mitotic Spindle Organization	Single Fertilization Ubiquitin-dependent ERAD Pathway
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Breast size ( 27182965) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		9 interacting genes: APP CDK1 ERRFI1 HSPB2 IDO1 NCOA3 PMEPA1 RPSA UBXN8	13 interacting genes: ADRB3 AQP6 C8orf86 DCTN6 GJA8 HSD17B13 MEOX2 PGRMC2 RBPMS SFRP1 SPCS1 TMEM14B WRN
Entrez ID		10671	7993
HPRD ID		09907	03692
Ensembl ID		ENSG00000104671	ENSG00000104691
Uniprot IDs		O00399	B4DKK1 O00124
PDB IDs		3TV0
Enriched GO Terms of Interacting Partners?
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