CXCL8 and ACKR1

  • Number of citations of the paper that reports this interaction (PubMedID 17416748)
  • 29
  • Data Source:
  • HPRD (in vitro, in vivo)

CXCL8

ACKR1

Description C-X-C motif chemokine ligand 8 atypical chemokine receptor 1 (Duffy blood group)
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Eotaxin levels ( 27989323)
  • Growth-regulated protein alpha levels ( 27989323)
  • Midgestational total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095)
  • Monocyte chemoattractant protein-1 levels ( 27989323 31217265)
  • Neutrophil level response to clozapine in treatment-resistant schizophrenia ( 30647433)
Interacting Genes 22 interacting genes: ACKR1 ARFGAP3 BAG6 CCL2 CCL4 CCL5 CCL8 CTSL CXCR1 CXCR2 EP300 ERBB2 GNAI2 IL12A MMP9 PF4 POMGNT1 SDC1 SGTA WASF1 ZFP36 ZNF598 10 interacting genes: CCL17 CCL2 CCL5 CCL7 CCL8 CD48 CXCL1 CXCL5 CXCL8 MTNR1B
Entrez ID 3576 2532
HPRD ID 00909 00192
Ensembl ID ENSG00000169429 ENSG00000213088
Uniprot IDs A0A024RDA5 P10145 Q16570 Q5Y7A1 Q5Y7A2
PDB IDs 1ICW 1IKL 1IKM 1IL8 1ILP 1ILQ 1QE6 1ROD 2IL8 3IL8 4XDX 5D14 5WDZ 6LFM 6LFO 6N2U 6WZM 4NUU 4NUV
Enriched GO Terms of Interacting Partners?
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