IL6ST and OSMR

  • Number of citations of the paper that reports this interaction (PubMedID 9188471)
  • 19
  • Data Source:
  • HPRD (in vitro)

IL6ST

OSMR

Description interleukin 6 cytokine family signal transducer oncostatin M receptor
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 29875488)
  • Central retinal vein equivalent ( 31597446)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 26192919 28067908)
  • Daytime sleep phenotypes ( 27126917)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Hemoglobin levels ( 32327693)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Immature fraction of reticulocytes ( 32888494)
  • Inflammatory bowel disease ( 26192919 28067908)
  • Microalbuminuria ( 26631737)
  • Night sleep phenotypes ( 27126917)
  • Obesity-related traits ( 23251661)
  • Postoperative survival time in hepatocellular carcinoma ( 30945673 30945699)
  • Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)
  • Reticulocyte fraction of red cells ( 32888494)
  • Ulcerative colitis ( 26192919 28067908)
Interacting Genes 35 interacting genes: AR CDK9 CMYA5 CNTF CNTFR CTF1 ERBB2 ERBB3 FBXO2 HCK IL31RA IL6 IL6R JAK1 KCNIP1 KCNIP3 LIF LIFR MAGEA11 OSM OSMR PIK3CG PLAUR PRKCD PTPN11 PTPN6 SGTA SGTB SHC1 SOCS3 STAT3 TLE1 TYK2 UBQLN1 VAV1 12 interacting genes: GAPDH GPRC5D IL6ST JAK1 JAK2 LHX2 MTDH OSM RGS4 SGTB SLC10A6 UBQLN2
Entrez ID 3572 9180
HPRD ID 02824 03446
Ensembl ID ENSG00000134352 ENSG00000145623
Uniprot IDs A0A0A0N0L2 P40189 Q17RA0 Q99650
PDB IDs 1BJ8 1BQU 1I1R 1N2Q 1P9M 1PVH 3L5H 3L5I 3L5J
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?