IL1RAP and IL1R2

  • Number of citations of the paper that reports this interaction (PubMedID 9862719)
  • 39
  • Data Source:
  • HPRD (in vivo)

IL1RAP

IL1R2

Description interleukin 1 receptor accessory protein interleukin 1 receptor type 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Ankylosing spondylitis ( 23749187 20062062)
  • Asthma ( 31619474)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blood protein levels ( 30072576 29875488)
  • C-reactive protein levels ( 30388399)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Fibrinogen ( 23969696)
  • Fibrinogen levels ( 28107422)
  • Inflammatory bowel disease ( 28067908 23128233)
  • Parkinson's disease ( 32201043 28892059)
  • Ulcerative colitis ( 21297633)
Interacting Genes 22 interacting genes: AP2M1 CCNI FXR1 IL18R1 IL1A IL1B IL1R1 IL1R2 IRAK1 KPNA1 MARCHF8 MC4R MYD88 PIK3R1 PRKCI PRPF40A PTPRD RAC1 SIRPA STAT3 TICAM2 TOLLIP 5 interacting genes: IL1A IL1B IL1RAP IL1RN USP15
Entrez ID 3556 7850
HPRD ID 04021 00995
Ensembl ID ENSG00000196083 ENSG00000115590
Uniprot IDs A8K6K4 Q9NPH3 P27930
PDB IDs 3O4O 4DEP 3O4O
Enriched GO Terms of Interacting Partners?
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