LCE3A and RGS17

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LCE3A	RGS17
Description		late cornified envelope 3A	regulator of G protein signaling 17
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Plasma Membrane Neuron Projection Synapse
	Molecular Function	Protein Binding	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Keratinization Killing Of Cells Of Other Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Catalytic Activity
Pathways		Formation of the cornified envelope	G alpha (q) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23727859) Inflammatory skin disease ( 25574825) Psoriasis ( 19169255) Psoriasis vulgaris ( 26626624)	Adult body size ( 32376654) Alcohol dependence ( 26365420) Apolipoprotein A1 levels ( 32203549) Bacterial meningitis ( 31092817) Body mass index ( 28892062) Cuneus cortex volume ( 31530798) Diastolic blood pressure ( 30224653) Fasting glucose ( 33402679 34059833) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 29083408) Lipoprotein (a) levels ( 26377243) Morning person ( 30696823) Pneumococcal meningitis ( 31092817) Prostate cancer ( 23535732) Triglyceride levels ( 32203549) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		61 interacting genes: ADAMTSL4 ALPP CHIC2 CYSRT1 EFEMP1 EFEMP2 FBLN1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1C LCE2A LCE2B LCE2C LCE3B MACO1 MDFI NBPF19 NOTCH2NLA OIT3 PLSCR2 RGS17 RGS20 SMCP SPRY1 SPRY3 TGFB1 TGM1 TRIM42 TSPAN4 VWC2 VWC2L	43 interacting genes: ADRB2 AQP1 BOLA2 BOLA2B CHRD CRCT1 CREB5 DHX37 GNAI1 GNAI3 HOXA1 HSD3B7 KRTAP4-11 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 LCE1A LCE1B LCE1D LCE1E LCE2A LCE2B LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A NUFIP2 OSTM1 OTX1 PTGER3 RABEP1 RBBP8 RPL10A SLC39A7 SMCP STUB1 TBC1D16 VASN
Entrez ID		353142	26575
HPRD ID		13973	06223
Ensembl ID		ENSG00000185962	ENSG00000091844
Uniprot IDs		Q5TA76	Q9UGC6
PDB IDs			1ZV4 6AM3
Enriched GO Terms of Interacting Partners?
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