RGS17 and TBC1D16

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		RGS17	TBC1D16
Description		regulator of G protein signaling 17	TBC1 domain family member 16
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Neuron Projection Synapse	Early Endosome Cytosol
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding	GTPase Activator Activity Protein Binding
	Biological Process	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Catalytic Activity	Regulation Of Receptor Recycling Intracellular Protein Transport Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events	TBC/RABGAPs
Drugs
Diseases
GWAS		Adult body size ( 32376654) Alcohol dependence ( 26365420) Apolipoprotein A1 levels ( 32203549) Bacterial meningitis ( 31092817) Body mass index ( 28892062) Cuneus cortex volume ( 31530798) Diastolic blood pressure ( 30224653) Fasting glucose ( 33402679 34059833) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 29083408) Lipoprotein (a) levels ( 26377243) Morning person ( 30696823) Pneumococcal meningitis ( 31092817) Prostate cancer ( 23535732) Triglyceride levels ( 32203549) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Albumin-globulin ratio ( 29403010) Hematology traits ( 30576415) Mean reticulocyte volume ( 32888494) Non-albumin protein levels ( 29403010) Serum total protein level ( 29403010)
Interacting Genes		43 interacting genes: ADRB2 AQP1 BOLA2 BOLA2B CHRD CRCT1 CREB5 DHX37 GNAI1 GNAI3 HOXA1 HSD3B7 KRTAP4-11 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 LCE1A LCE1B LCE1D LCE1E LCE2A LCE2B LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A NUFIP2 OSTM1 OTX1 PTGER3 RABEP1 RBBP8 RPL10A SLC39A7 SMCP STUB1 TBC1D16 VASN	16 interacting genes: CYGB GABARAPL1 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP4-12 KRTAP5-9 MAP1LC3A NOTCH2NLA PSMA3 RGS17 RGS20 TNS2 TRAF1
Entrez ID		26575	125058
HPRD ID		06223	10261
Ensembl ID		ENSG00000091844	ENSG00000167291
Uniprot IDs		Q9UGC6	Q8TBP0
PDB IDs		1ZV4 6AM3
Enriched GO Terms of Interacting Partners?
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