IGHM and VPREB1

Number of citations of the paper that reports this interaction (PubMedID 2117639)
46

Data Source:
HPRD (in vitro)

		IGHM	VPREB1
Description		immunoglobulin heavy constant mu	V-set pre-B cell surrogate light chain 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane Immunoglobulin Complex, Circulating Extracellular Exosome Pentameric IgM Immunoglobulin Complex Hexameric IgM Immunoglobulin Complex Blood Microparticle	Extracellular Region Extracellular Space Endoplasmic Reticulum
	Molecular Function	Single-stranded DNA Binding Antigen Binding Phosphatidylcholine Binding Immunoglobulin Receptor Binding Peptidoglycan Binding
	Biological Process	Adaptive Immune Response Phagocytosis, Recognition Phagocytosis, Engulfment Complement Activation, Classical Pathway Antibacterial Humoral Response Defense Response To Bacterium Innate Immune Response Defense Response To Gram-negative Bacterium B Cell Receptor Signaling Pathway Positive Regulation Of B Cell Activation	Immunoglobulin Production Immune Response
Pathways			Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Systemic sclerosis ( 33069728)	Diastolic blood pressure ( 29208002) Periodontitis (PAL4Q3) ( 24024966) Response to selective serotonin reuptake inhibitors in depression ( 27622933)
Interacting Genes		19 interacting genes: APP CD22 CD79A CEP72 GADD45A GSK3B HPR HSPA5 JCHAIN MAP3K20 MAPKAPK3 PTK2 SH3GL2 SMN1 TK1 UBQLN4 UFD1 VPREB1 VPREB3	3 interacting genes: IGHM LGALS1 VPREB3
Entrez ID		3507	7441
HPRD ID		00912	05505
Ensembl ID		ENSG00000211899	ENSG00000169575
Uniprot IDs			F8W8C9 P12018
PDB IDs			2H32 2H3N 3BJ9
Enriched GO Terms of Interacting Partners?
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