CYP2C18 and A2M

  • Number of citations of the paper that reports this interaction (PubMedID 21163940)
  • 36
  • Data Source:
  • BioGRID (two hybrid)

CYP2C18

A2M

Description cytochrome P450 family 2 subfamily C member 18 alpha-2-macroglobulin
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acenocoumarol maintenance dosage ( 19578179)
  • Clopidogrel active metabolite levels ( 28207573)
  • Common carotid intima-media thickness in HIV negative individuals ( 29206233)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Red cell distribution width ( 32888494)
  • Response to clopidogrel therapy ( 28207573 19706858)
  • Serum alkaline phosphatase levels ( 33547301)
  • Serum metabolite levels ( 23093944)
  • Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122)
  • Warfarin maintenance dose ( 23755828)
  • Warfarin maintenance dose (adjusted for clinical factors) ( 28686080)
Interacting Genes 6 interacting genes: A2M APOE ECSIT KMT2E PSEN1 SDC2 98 interacting genes: ACTB ADAM19 ADAMTS1 AMBP ANXA6 ANXA7 AP1M2 APOE APP ATF7IP ATP1A1 B2M C11orf58 CDC37 CDC42 CDK2AP2 CDKN1A CELA1 CPB2 CTSB CTSE CYP2C18 CYP2C8 DNAJB1 ECSIT EGLN2 ELAVL3 ENO2 EVI5L EXOSC1 FARSA FBXL12 FBXW4 FIS1 GCDH GEM GRB2 H2AX HMOX2 HSP90AA1 HSPA5 HSPB2 IFIT3 IFIT5 IGSF8 IL10 IL1B IL4 KLK1 KLK13 KLK2 KLK3 LCAT LEP LINC02582 LONP1 LRP1 LYZ MAST1 MLST8 MMP2 MYOC NCDN NGF NOS3 NUDT21 OGA PAEP PAXIP1 PDGFA PDGFB PRAM1 PRDX2 RAB3A RAD23A RAP1B RETN RHEB RNF32 RPP14 SEPTIN8 SHBG SLC6A4 SMN1 STAMBPL1 SWSAP1 TGFBI TGIF1 TGM2 TK1 TNFRSF14 TRAPPC5 TSC22D1 TTR TUBA1B TYRO3 UFD1 UMPS
Entrez ID 1562 2
HPRD ID 03085 00072
Ensembl ID ENSG00000108242 ENSG00000175899
Uniprot IDs P33260 Q7Z348 P01023
PDB IDs 2CIK 2H6P 1BV8 2P9R 4ACQ
Enriched GO Terms of Interacting Partners?
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