NCKAP5 and APC

  • Number of citations of the paper that reports this interaction (PubMedID 20936779)
  • 88
  • Data Source:
  • BioGRID (two hybrid)

NCKAP5

APC

Description NCK associated protein 5 APC regulator of WNT signaling pathway
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (survival time) ( 25649651)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cognitive performance (processing speed) ( 31598132)
  • Cortical surface area (MOSTest) ( 32665545)
  • Cortical thickness (MOSTest) ( 32665545)
  • Diastolic blood pressure x dichotomous lifestyle risk score interaction (1df test) ( 32227373)
  • Diastolic blood pressure x dichotomous lifestyle risk score interaction (2df test) ( 32227373)
  • Glaucoma (primary open-angle) ( 22419738)
  • Gout (combined type) ( 32238385)
  • Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
  • Height ( 20881960)
  • Homeostasis model assessment of insulin resistance ( 33381925)
  • Hypersomnia (HLA-DQB1*06:02 negative) ( 23646285)
  • Initial pursuit acceleration ( 29064472)
  • Iron status biomarkers (iron levels) ( 28334935)
  • LDL cholesterol levels in HIV infection ( 33109212)
  • Lingual gyrus volume ( 31530798)
  • Optic disc size ( 31809533)
  • PR interval ( 32439900)
  • Rosacea symptom severity ( 29771307)
  • Selective IgA deficiency ( 27723758)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
Interacting Genes 3 interacting genes: APC NCK1 VAV2 138 interacting genes: ACTN1 ADGRL1 AGFG1 AGR3 ANKRD17 ANP32B ANXA7 AP2B1 ARHGEF4 ASAP2 AXIN1 AXIN2 BAAT BUB1 BUB1B C4A CASC3 CCL5 CGNL1 COG4 COG5 CREBBP CSNK1A1 CSNK1E CTBP1 CTNNB1 CTSV CYP17A1 CYTH2 DIRAS3 DKK3 DLG3 DLGAP1 DST EPAS1 ERBIN EXPH5 FAM214A FANCC FBP1 FBXO30 FHOD1 FLNA GIGYF2 GOLGA2 GSK3B HGS HNRNPM HOXC6 HPCA HSPA5 HTRA2 IL24 ING5 IQGAP1 JUP KIAA1328 KIF5B KIFAP3 KRT13 KRT14 KRT15 KRT17 KRT23 KRT5 LAMA3 LAMA4 MACF1 MAN2A1 MAP2K1 MAPRE1 MAPRE2 MBD5 MCM3AP MKRN1 MT-ND4 MUC1 MYH10 MYH11 MYO6 NANS NAT2 NAV1 NAV2 NAV3 NCKAP5 NCKAP5L NEB NOSTRIN NUP153 NUP214 NUP42 NUP54 NUP58 NUP98 PDLIM2 PNISR POM121 POM121C PPP1R13B PPP2CA PPP2R5A PPP3R2 PRKACA PSMD1 PTPN13 RANBP9 RASA1 RBM4B RP1 RPS27 SCRIB SEC31A SETDB1 SIAH1 SMAD1 SMC3 SNRNP200 SPECC1L SPTBN1 SPTBN2 ST14 SYNE1 TAF1 TFAP2A TFF1 TGFB1 TMEFF1 TMOD1 TPR TRIM21 TRIM25 TSTD2 TUBA4A XPO1 YWHAQ ZNF106 ZNF510
Entrez ID 344148 324
HPRD ID 19275 01439
Ensembl ID ENSG00000176771 ENSG00000134982
Uniprot IDs O14513 P25054 Q4LE70
PDB IDs 1DEB 1EMU 1JPP 1M5I 1T08 1TH1 1V18 2RQU 3AU3 3NMW 3NMX 3NMZ 3QHE 3RL7 3RL8 3T7U 4G69 4YJE 4YJL 4YK6 5B6G 5IZ6 5IZ8 5IZ9 5IZA 5Z8H
Enriched GO Terms of Interacting Partners?
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