IDI1 and TXNIP

Number of citations of the paper that reports this interaction (PubMedID 31669268)
4

Data Source:
BioGRID (two hybrid)

		IDI1	TXNIP
Description		isopentenyl-diphosphate delta isomerase 1	thioredoxin interacting protein
Image
GO Annotations	Cellular Component	Cytoplasm Peroxisome Cytosol	Nucleus Cytoplasm Mitochondrial Intermembrane Space Cytosol
	Molecular Function	Isopentenyl-diphosphate Delta-isomerase Activity Metal Ion Binding	Enzyme Inhibitor Activity Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Cholesterol Biosynthetic Process Isopentenyl Diphosphate Biosynthetic Process Dimethylallyl Diphosphate Biosynthetic Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Import Into Nucleus Cell Cycle Response To Xenobiotic Stimulus Response To Mechanical Stimulus Response To Glucose Protein Transport Keratinocyte Differentiation Response To Estradiol Response To Progesterone Regulation Of Cell Population Proliferation Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Platelet-derived Growth Factor Receptor Signaling Pathway Response To Calcium Ion Negative Regulation Of Cell Division Cellular Response To Tumor Cell
Pathways		Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)	The NLRP3 inflammasome The NLRP3 inflammasome Regulation of FOXO transcriptional activity by acetylation Purinergic signaling in leishmaniasis infection Purinergic signaling in leishmaniasis infection Cytoprotection by HMOX1
Drugs		Dimethylallyl Diphosphate
Diseases
GWAS
Interacting Genes		6 interacting genes: BARD1 LARP4B PITRM1 TXNIP WT1 ZNF655	28 interacting genes: CBX8 DDIT4 ECD EEF1A1 FHL1 GAPDH HDAC1 HDAC3 HSPB2 IDI1 INTS9 KPNA2 LUC7L3 MAPK1 NLGN3 PRKAA1 PTPN11 RUVBL2 SCEL SIVA1 SMURF2 TRAF6 TXN TXNRD1 UBR5 UXT ZBTB16 ZBTB32
Entrez ID		3422	10628
HPRD ID		07235	05964
Ensembl ID		ENSG00000067064	ENSG00000265972
Uniprot IDs		Q13907	Q9H3M7
PDB IDs		2DHO 2I6K 2ICJ 2ICK	4GEI 4GEJ 4GFX 4LL1 4LL4 4ROF 4ROJ 5CQ2 5DF6 5DWS 5DZD
Enriched GO Terms of Interacting Partners?
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