TXNIP and IDI1

Number of citations of the paper that reports this interaction (PubMedID 31669268)
4

Data Source:
BioGRID (two hybrid)

		TXNIP	IDI1
Description		thioredoxin interacting protein	isopentenyl-diphosphate delta isomerase 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrial Intermembrane Space Cytosol	Cytoplasm Peroxisome Cytosol
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Ubiquitin Protein Ligase Binding	Isopentenyl-diphosphate Delta-isomerase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Import Into Nucleus Cell Cycle Response To Xenobiotic Stimulus Response To Mechanical Stimulus Response To Glucose Protein Transport Keratinocyte Differentiation Response To Estradiol Response To Progesterone Regulation Of Cell Population Proliferation Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Platelet-derived Growth Factor Receptor Signaling Pathway Response To Calcium Ion Negative Regulation Of Cell Division Cellular Response To Tumor Cell	Cholesterol Biosynthetic Process Isopentenyl Diphosphate Biosynthetic Process Dimethylallyl Diphosphate Biosynthetic Process
Pathways		The NLRP3 inflammasome The NLRP3 inflammasome Regulation of FOXO transcriptional activity by acetylation Purinergic signaling in leishmaniasis infection Purinergic signaling in leishmaniasis infection Cytoprotection by HMOX1	Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs			Dimethylallyl Diphosphate
Diseases
GWAS
Interacting Genes		28 interacting genes: CBX8 DDIT4 ECD EEF1A1 FHL1 GAPDH HDAC1 HDAC3 HSPB2 IDI1 INTS9 KPNA2 LUC7L3 MAPK1 NLGN3 PRKAA1 PTPN11 RUVBL2 SCEL SIVA1 SMURF2 TRAF6 TXN TXNRD1 UBR5 UXT ZBTB16 ZBTB32	6 interacting genes: BARD1 LARP4B PITRM1 TXNIP WT1 ZNF655
Entrez ID		10628	3422
HPRD ID		05964	07235
Ensembl ID		ENSG00000265972	ENSG00000067064
Uniprot IDs		Q9H3M7	Q13907
PDB IDs		4GEI 4GEJ 4GFX 4LL1 4LL4 4ROF 4ROJ 5CQ2 5DF6 5DWS 5DZD	2DHO 2I6K 2ICJ 2ICK
Enriched GO Terms of Interacting Partners?
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