C2orf74 and PNPT1

		C2orf74	PNPT1
Description		chromosome 2 open reading frame 74	polyribonucleotide nucleotidyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nucleus Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix Endoplasmic Reticulum Membrane Cytosol Polysomal Ribosome Mitochondrial Degradosome
	Molecular Function	Protein Binding	3'-5'-exoribonuclease Activity RNA Binding Polyribonucleotide Nucleotidyltransferase Activity Protein Binding Poly(U) RNA Binding Poly(G) Binding MiRNA Binding
	Biological Process		Mitochondrial RNA Catabolic Process Mitochondrial MRNA Catabolic Process Positive Regulation Of Mitochondrial RNA Catabolic Process Mitochondrial RNA 5'-end Processing Mitochondrial RNA 3'-end Processing RNA Catabolic Process MRNA Catabolic Process Cellular Response To Oxidative Stress Cellular Response To Interferon-beta RNA Import Into Mitochondrion RRNA Import Into Mitochondrion Regulation Of Cellular Respiration RNA Polyadenylation Negative Regulation Of Growth Protein Homooligomerization Response To CAMP Regulation Of Cell Cycle Response To Growth Hormone Positive Regulation Of MRNA Catabolic Process Protein Homotrimerization Mitochondrion Morphogenesis Nuclear Polyadenylation-dependent MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Mitochondrial MRNA Polyadenylation Liver Regeneration Positive Regulation Of MiRNA Catabolic Process Regulation Of Cellular Senescence
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 22412388 21102463) High light scatter reticulocyte percentage of red cells ( 32888494) Inflammatory bowel disease ( 23128233)	Autoimmune thyroid disease ( 32581359) Diastolic blood pressure ( 27618452) Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 33627673 29891935) Height ( 28552196 25429064 18391951) Hip circumference adjusted for BMI ( 34021172) Intraocular pressure ( 29617998 31959993) Medication use (antiglaucoma preparations and miotics) ( 31015401) Medication use (thyroid preparations) ( 31015401) Optic cup area ( 28073927) Pulse pressure ( 28135244 27841878) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 27618452) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist circumference adjusted for body mass index ( 28552196 34021172) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549) White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes		6 interacting genes: AHSA2P COMMD1 PNPT1 POT1 SMAGP TMEM17	4 interacting genes: ADARB1 C2orf74 HSPB1 WDPCP
Entrez ID		339804	87178
HPRD ID		19550	18493
Ensembl ID		ENSG00000237651	ENSG00000138035
Uniprot IDs		A8MZ97 C9JBF1	Q8TCS8
PDB IDs			3U1K 5ZF6
Enriched GO Terms of Interacting Partners?
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