RXFP4 and RLN3

Number of citations of the paper that reports this interaction (PubMedID 14522967)
40

Data Source:
HPRD (in vivo)

		RXFP4	RLN3
Description		relaxin family peptide/INSL5 receptor 4	relaxin 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region
	Molecular Function	Protein Binding G Protein-coupled Peptide Receptor Activity	G Protein-coupled Receptor Binding Hormone Activity Protein Binding
	Biological Process	Neuropeptide Signaling Pathway Positive Regulation Of Feeding Behavior	Signal Transduction
Pathways		G alpha (i) signalling events Relaxin receptors	G alpha (s) signalling events G alpha (i) signalling events Relaxin receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 34021172)	Obesity-related traits ( 23251661)
Interacting Genes		10 interacting genes: ACTR10 GAPDH GJA8 KNG1 MAGED1 QDPR RLN3 TSPAN3 TTC4 TTI1	4 interacting genes: ODAD3 RXFP1 RXFP3 RXFP4
Entrez ID		339403	117579
HPRD ID		16421	06031
Ensembl ID		ENSG00000173080	ENSG00000171136
Uniprot IDs		Q8TDU9	B2RU28 K7ENX1 Q8WXF3
PDB IDs			2FHW 2K1V
Enriched GO Terms of Interacting Partners?
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