HSF4 and CDK2AP2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		HSF4	CDK2AP2
Description		heat shock transcription factor 4	cyclin dependent kinase 2 associated protein 2
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GO Annotations	Cellular Component	Chromatin Nucleus Nuclear Speck	Nucleus Cytoplasm Microtubule
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Identical Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Visual Perception Positive Regulation Of Cell Population Proliferation Histone H3-K9 Demethylation Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cell Development Lens Fiber Cell Differentiation	Regulation Of Microtubule Cytoskeleton Organization Regulation Of Stem Cell Division Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS
Interacting Genes		46 interacting genes: AKAP8L ALKBH4 BBS2 C10orf55 C19orf54 CDK2AP2 CNOT1 DAXX DUSP26 FAM168B FOXH1 FOXI1 GFOD1 HGS INTS11 KRT31 KRT37 KRT38 KRT40 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP6-2 MAPK1 MAPK14 MAPK3 MAPK8 MKRN3 NHLRC4 NUDT21 NUP62 OIP5 PIH1D2 PITX1 PLA2G10 PPFIBP2 SESTD1 SLC27A5 SMARCA4 SOX10 STOML2 TPM3 UFSP1 YTHDF1 ZBED8 ZMYND12	17 interacting genes: A2M APP CDK2AP1 DBN1 EED EEF1G HSF4 IKZF1 MBTPS1 MRFAP1L1 PYCR1 RCC1 RPLP1 TRA2A WARS1 YIF1A ZBTB48
Entrez ID		3299	10263
HPRD ID		03896	13242
Ensembl ID		ENSG00000102878	ENSG00000167797
Uniprot IDs		A0A024R6X7 Q9ULV5	O75956 Q6IAV4
PDB IDs		6J6V 6J6W	2M1L
Enriched GO Terms of Interacting Partners?
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