CDK2AP2 and RCC1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		CDK2AP2	RCC1
Description		cyclin dependent kinase 2 associated protein 2	regulator of chromosome condensation 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule	Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Cytoplasm Nuclear Membrane Protein-containing Complex
	Molecular Function	Protein Binding	Chromatin Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Nucleosome Binding Nucleosomal DNA Binding Histone Binding Sulfate Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Microtubule Cytoskeleton Organization Regulation Of Stem Cell Division Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Mitotic Nuclear Membrane Reassembly Regulation Of Mitotic Nuclear Division Viral Process Regulation Of Catalytic Activity Spindle Assembly Cell Division
Pathways			Rev-mediated nuclear export of HIV RNA Nuclear import of Rev protein Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS			Night sleep phenotypes ( 27126917) Systolic blood pressure ( 30578418)
Interacting Genes		17 interacting genes: A2M APP CDK2AP1 DBN1 EED EEF1G HSF4 IKZF1 MBTPS1 MRFAP1L1 PYCR1 RCC1 RPLP1 TRA2A WARS1 YIF1A ZBTB48	51 interacting genes: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 ERCC6 FAF1 FBXO7 FLAD1 GNB2 H2AC18 H2AC20 H2BC21 H3C1 HADHB HMGA1 HOXD8 KMT2B KPNA3 KPNA4 LRIF1 NGFR NTMT1 NUDT21 NUP98 OGT PDHB PKM PTMA RAN RANBP1 RANBP3 RPA1 SDF4 SPRED1 SUMO2 TLE1 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135
Entrez ID		10263	1104
HPRD ID		13242	01559
Ensembl ID		ENSG00000167797	ENSG00000180198
Uniprot IDs		O75956 Q6IAV4	A0A0S2Z3I4 A0A0S2Z404 P18754 Q5T081
PDB IDs		2M1L	1A12 1I2M 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 5TBK 6DUB
Enriched GO Terms of Interacting Partners?
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