HPX and GLUD1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		HPX	GLUD1
Description		hemopexin	glutamate dehydrogenase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Collagen-containing Extracellular Matrix Extracellular Exosome Endocytic Vesicle Lumen Blood Microparticle	Cytoplasm Mitochondrion Mitochondrial Matrix Endoplasmic Reticulum
	Molecular Function	Protein Binding Heme Transmembrane Transporter Activity Metal Ion Binding	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Glutamate Dehydrogenase (NADP+) Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding ADP Binding NAD+ Binding Leucine Binding
	Biological Process	Positive Regulation Of Immunoglobulin Production Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Cellular Iron Ion Homeostasis Heme Transport Hemoglobin Metabolic Process Heme Metabolic Process Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Interferon-gamma-mediated Signaling Pathway	Glutamate Biosynthetic Process Glutamate Catabolic Process Glutamine Metabolic Process Substantia Nigra Development Positive Regulation Of Insulin Secretion Tricarboxylic Acid Metabolic Process
Pathways		Scavenging of heme from plasma	Transcriptional activation of mitochondrial biogenesis Glutamate and glutamine metabolism
Drugs		Zinc chloride Zinc sulfate, unspecified form	Glutamic acid NADH Hexachlorophene Guanosine-5'-Triphosphate Aluminum chloride
Diseases
GWAS		Blood protein levels ( 29875488) Malaria ( 31844061)	Renal underexcretion gout ( 32238385)
Interacting Genes		4 interacting genes: GLUD1 HSP90AA1 LINC02582 TP63	13 interacting genes: ASGR2 CRP CTNNB1 DYNLL1 GOT2 HPX HSD17B10 LSM1 NR4A1 OGT ORM1 STAT5A VTN
Entrez ID		3263	2746
HPRD ID		00793	11748
Ensembl ID		ENSG00000110169	ENSG00000148672
Uniprot IDs		P02790 Q9BS19	E9KL48 P00367
PDB IDs			1L1F 1NR1 6DQG
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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