HPR and VKORC1

  • Number of citations of the paper that reports this interaction (PubMedID 21103663)
  • 9
  • Data Source:
  • BioGRID (two hybrid)

HPR

VKORC1

Description haptoglobin-related protein vitamin K epoxide reductase complex subunit 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase levels ( 34315874)
  • Apolipoprotein A1 levels ( 33730874)
  • Aspartate aminotransferase levels ( 33547301 34315874)
  • Blood protein levels ( 28240269)
  • Cholesterol, total ( 24097068 28270201 25961943 20686565 26582766)
  • Coronary artery disease ( 32469254 33020668)
  • Hematocrit ( 32888494)
  • LDL cholesterol ( 24097068 25961943 20686565 26582766)
  • LDL cholesterol levels ( 28334899 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Liver enzyme levels (alkaline phosphatase) ( 22001757)
  • Low density lipoprotein cholesterol levels ( 32154731 33339817)
  • Metabolite levels ( 22916037)
  • Serum metabolite levels ( 31636271)
  • Serum metabolite levels (CMS) ( 31636271)
  • Total cholesterol levels ( 28334899)
  • Triglyceride levels ( 32154731)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes 6 interacting genes: APOA1 DYNC1LI2 HSP90AA1 IGHM PSKH1 VKORC1 94 interacting genes: AHSG APLP2 APOA1 APOA2 APOC1 APOC3 APOC4 ARL6IP5 ASGR1 ASGR2 ATP5MC3 ATP6AP2 BCAP31 C1S CCDC12 CCDC167 CD63 CD81 CD9 CLDN10 CNN3 COMT CPLX4 CREB3 CREB3L1 CXADR DCTPP1 DPM2 ECHDC1 FAM209A FAM210B FGG FGL1 FIS1 FTL GJB1 GORAB GPR152 HAMP HDAC6 HOMER2 HP HPR HSD17B7 IFITM3 JAGN1 KCNK17 LIG4 LMNA MANBAL METTL7B MSMO1 MSRB1 MT1X MUC1 PCDH1 PCMT1 PDIA6 PIGH PLP2 PPA2 PPIB PROCR REEP5 RMDN1 RMDN3 RMND5A SAA1 SAT1 SERPINA1 SLC15A3 SLC22A2 SLC25A1 SLC31A2 SLC7A14 SNORA12 SPTSSA STAT6 SURF4 TF TMBIM4 TMEM120A TMEM134 TMEM176A TMEM230 TMEM242 TMEM256 TMEM35B TMEM45B TRAM1 TREX1 VAPB YIF1A ZCCHC24
Entrez ID 3250 79001
HPRD ID 00773 10540
Ensembl ID ENSG00000261701 ENSG00000167397
Uniprot IDs P00739 A0A0S2Z5X7 A0A0S2Z6I4 Q9BQB6
PDB IDs 6WV3 6WV4 6WV5 6WV6 6WV7 6WVH
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?