HOXD4 and DEDD

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		HOXD4	DEDD
Description		homeobox D4	death effector domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cell Junction	Nucleolus Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Anterior/posterior Pattern Specification Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis	Spermatogenesis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Protein Catabolic Process Regulation Of Apoptotic Process Decidualization Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Male-pattern baldness ( 28196072) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		21 interacting genes: ASB8 CNOT7 CREBBP DEDD EP300 ETV4 FANCL HIPK1 HNRNPAB HOXB13 MEIS1 PBX1 PBX4 RNPS1 RXRG SNAI1 TIGD4 XRCC6 ZBTB32 ZMYND11 ZSCAN18	24 interacting genes: APLP2 APP BATF2 CASP10 CASP3 CASP8 CFLAR DEDD2 FADD GTF3C1 GTF3C3 HOXD4 IRF9 KRT18 KRT8 MPZ NR1I3 PRRC2C SDHC SHMT1 SLC19A2 SMAD3 UAP1 VPS26A
Entrez ID		3233	9191
HPRD ID		00864	06022
Ensembl ID		ENSG00000170166	ENSG00000158796
Uniprot IDs		P09016	B1AQP5 O75618
PDB IDs
Enriched GO Terms of Interacting Partners?
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