HOXC9 and HOXC13

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		HOXC9	HOXC13
Description		homeobox C9	homeobox C13
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Aggresome	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Embryonic Skeletal System Morphogenesis	Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Body shape index ( 34021172) Heel bone mineral density ( 30598549) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs) ( 23648065) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Biliary atresia ( 20460270) Blond vs. brown/black hair color ( 30531825) Body shape index ( 34021172) Hair shape ( 29220522) Hip circumference adjusted for BMI ( 34021172) Toenail selenium levels ( 25343990) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 25673412 20935629) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes		29 interacting genes: CBX6 CYSRT1 ELAVL2 GMNN GTF2A1L HOXC13 HOXD1 HOXD9 IRF9 KRTAP6-2 LPXN MAGED1 MSX2 NFKBID NMI PAX6 PAX8 PBX2 PCGF2 POLR2D POLR3D POU2AF1 POU2F1 TEX37 TLE5 UFSP1 ZFP36 ZMYND12 ZNF384	7 interacting genes: APEX1 ELF1 HNRNPAB HOXC9 MEIS1 NR2E3 RHOXF2
Entrez ID		3225	3229
HPRD ID		00857	00862
Ensembl ID		ENSG00000180806	ENSG00000123364
Uniprot IDs		A0A024RAZ6 P31274	P31276
PDB IDs		2LP0 2MSY
Enriched GO Terms of Interacting Partners?
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