HOXC13 and ELF1

Number of citations of the paper that reports this interaction (PubMedID 18692240)
4

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		HOXC13	ELF1
Description		homeobox C13	E74 like ETS transcription factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Nucleus Nucleoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways			RUNX1 regulates transcription of genes involved in BCR signaling RUNX1 regulates transcription of genes involved in interleukin signaling
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs) ( 23648065) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Biliary atresia ( 20460270) Blond vs. brown/black hair color ( 30531825) Body shape index ( 34021172) Hair shape ( 29220522) Hip circumference adjusted for BMI ( 34021172) Toenail selenium levels ( 25343990) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 25673412 20935629) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)	Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) Cervical cancer ( 28806749) Crohn's disease ( 23266558) Eosinophil percentage of white cells ( 32888494) Height ( 31562340) Keratoconus ( 33649486) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494) Spleen volume ( 34128465) Systemic lupus erythematosus ( 27399966 23273568 33272962 21044949) Total cholesterol levels ( 30275531)
Interacting Genes		7 interacting genes: APEX1 ELF1 HNRNPAB HOXC9 MEIS1 NR2E3 RHOXF2	12 interacting genes: CD27 HMGA1 HOXC13 NFE2L2 NFKB1 NFYA NFYB NFYC RB1 REL RUNX1 SP1
Entrez ID		3229	1997
HPRD ID		00862	01808
Ensembl ID		ENSG00000123364	ENSG00000120690
Uniprot IDs		P31276	A0A024RDU6 P32519 Q6MZZ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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