GYPA and ELOVL4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GYPA	ELOVL4
Description		glycophorin A (MNS blood group)	ELOVL fatty acid elongase 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane	Endoplasmic Reticulum Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Virus Receptor Activity Protein Binding Identical Protein Binding	Protein Binding G Protein-coupled Photoreceptor Activity Fatty Acid Elongase Activity 3-oxo-arachidoyl-CoA Synthase Activity 3-oxo-cerotoyl-CoA Synthase Activity 3-oxo-lignoceronyl-CoA Synthase Activity Very-long-chain 3-ketoacyl-CoA Synthase Activity
	Biological Process	Viral Entry Into Host Cell	Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Detection Of Visible Light Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process
Pathways		Cell surface interactions at the vascular wall	Synthesis of very long-chain fatty acyl-CoAs
Drugs			Omega-3-carboxylic acids
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder (body mass index interaction) ( 24322204) Blood pressure (smoking interaction) ( 25189868) Chronic obstructive pulmonary disease ( 30804561 25101718) Diabetic neuropathy in type 2 diabetes ( 33430853) Diastolic blood pressure ( 27841878) Femoral neck bone mineral density ( 30172743) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Lung function (low FEV1 vs high FEV1) ( 26423011) Major depressive disorder x sex interaction ( 34099189) Malaria ( 31844061) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494 27863252) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Recurrent major depressive disorder x sex interaction ( 34099189) Red blood cell count ( 29403010) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Severe malaria ( 26416757) Systolic blood pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) White blood cell count ( 32888494)	Aging ( 22773346) Body mass index ( 23669352) Chronic obstructive pulmonary disease ( 28166215) Daytime sleep phenotypes ( 27126917) Hip circumference adjusted for BMI ( 34021172) Macular thickness ( 30535121) Partial epilepsies ( 20522523) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		25 interacting genes: ANKRD29 CLDN5 CREB3 CUL3 ELOVL4 ERGIC3 EVA1A FAM209A FFAR2 GOLT1A GPRC5D GPX8 KEAP1 LAPTM5 PDZK1IP1 SAR1A SGTA SGTB SLC10A6 TLCD4 TMBIM6 TMEM14B TMEM154 TMEM237 TMEM31	95 interacting genes: ADGRE2 ANKRD46 APOL3 ATP13A1 BCL2L1 BET1 BIK BNIP1 BNIP3 BTN2A2 C1GALT1 CCDC167 CCL4L2 CD70 CLCA4 CLDND2 CMTM3 CMTM5 CMTM7 COL4A5 CYB5R3 CYP4F2 ERG28 FA2H FAM177A1 FAM3C FAXDC2 FDFT1 FKBP8 FXYD6 GIMAP1 GIMAP5 GOSR2 GPR37L1 GYPA HMOX1 HMOX2 HSD3B7 IER3IP1 ITGAM JAGN1 LEPROTL1 LHFPL5 LY6D MALL MMP14 NINJ2 ORMDL2 ORMDL3 PKMYT1 PLLP PLN PLP1 PTPN1 RAB18 RTP2 SEC22A SEC22B SERF1A SERF1B SERP2 SFT2D2 SLC30A3 SLC30A8 SNORC STX3 SYNDIG1 TECR TF TMEM11 TMEM128 TMEM19 TMEM199 TMEM203 TMEM218 TMEM222 TMEM242 TMEM243 TMEM254 TMEM42 TMEM44 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 VAMP1 VAMP3 VAMP4 VAMP5 VAPB YIF1A YIPF6 ZDHHC21 ZFPL1
Entrez ID		2993	6785
HPRD ID		07508	05697
Ensembl ID		ENSG00000170180	ENSG00000118402
Uniprot IDs		A0A0C4DFT7 A0A2R8Y7F9 E9PD10 P02724 Q14419	Q9GZR5
PDB IDs		1AFO 1MSR 2KPE 2KPF 5EH4 5EH6
Enriched GO Terms of Interacting Partners?
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