GYPA and GPRC5D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GYPA	GPRC5D
Description		glycophorin A (MNS blood group)	G protein-coupled receptor class C group 5 member D
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome
	Molecular Function	Virus Receptor Activity Protein Binding Identical Protein Binding	G Protein-coupled Receptor Activity Protein Binding Protein Kinase Activator Activity
	Biological Process	Viral Entry Into Host Cell	G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase Activity
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder (body mass index interaction) ( 24322204) Blood pressure (smoking interaction) ( 25189868) Chronic obstructive pulmonary disease ( 30804561 25101718) Diabetic neuropathy in type 2 diabetes ( 33430853) Diastolic blood pressure ( 27841878) Femoral neck bone mineral density ( 30172743) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Lung function (low FEV1 vs high FEV1) ( 26423011) Major depressive disorder x sex interaction ( 34099189) Malaria ( 31844061) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494 27863252) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Recurrent major depressive disorder x sex interaction ( 34099189) Red blood cell count ( 29403010) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Severe malaria ( 26416757) Systolic blood pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) White blood cell count ( 32888494)
Interacting Genes		25 interacting genes: ANKRD29 CLDN5 CREB3 CUL3 ELOVL4 ERGIC3 EVA1A FAM209A FFAR2 GOLT1A GPRC5D GPX8 KEAP1 LAPTM5 PDZK1IP1 SAR1A SGTA SGTB SLC10A6 TLCD4 TMBIM6 TMEM14B TMEM154 TMEM237 TMEM31	31 interacting genes: APOL3 BTN2A2 C14orf180 C1GALT1 CCL4 EMP1 ERC1 ERMP1 FXYD3 FXYD6-FXYD2 GYPA IFITM3 IGFBP5 LHFPL5 LRRC25 MS4A6A OSMR PMP22 PRRT2 PVR SLC30A2 SLC66A1 SYNDIG1 TMEM120B TMEM19 TMEM208 TMEM79 TRARG1 TWSG1 UNC93B1 YIPF1
Entrez ID		2993	55507
HPRD ID		07508	07604
Ensembl ID		ENSG00000170180	ENSG00000111291
Uniprot IDs		A0A0C4DFT7 A0A2R8Y7F9 E9PD10 P02724 Q14419	Q9NZD1
PDB IDs		1AFO 1MSR 2KPE 2KPF 5EH4 5EH6
Enriched GO Terms of Interacting Partners?
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