PHPT1 and PPP1R16A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PHPT1	PPP1R16A
Description		phosphohistidine phosphatase 1	protein phosphatase 1 regulatory subunit 16A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Nuclear Body Extracellular Exosome	Plasma Membrane
	Molecular Function	Protein Binding Calcium Channel Inhibitor Activity Transmembrane Transporter Binding Protein Histidine Phosphatase Activity	Protein Binding Protein Phosphatase 1 Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity
	Biological Process	Protein Dephosphorylation Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Peptidyl-histidine Dephosphorylation Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of Lyase Activity Positive Regulation Of Cell Motility Regulation Of Actin Cytoskeleton Reorganization Negative Regulation Of ATP Citrate Synthase Activity	Regulation Of Protein Dephosphorylation Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS			Age at first birth ( 27798627) Blood metabolite levels ( 26401656) Educational attainment ( 25201988) Height ( 28552196) Mean corpuscular hemoglobin concentration ( 32888494 27863252)
Interacting Genes		8 interacting genes: ATXN1 ATXN1L CDC42 DNMT3L ERBB3 PPP1R16A TINF2 UBC	52 interacting genes: ANTKMT ATP23 ATXN7L2 AVPI1 BATF2 C1orf216 C3orf36 CCDC116 CDCA7L CDH24 CKMT1A CKMT1B DDX27 FSD1 HDAC7 HGS HLA-E IDO1 IL16 KAT5 KRTAP19-5 LY6H LZTS2 MCCD1 MRPL12 MYOM1 NDUFAB1 NEK6 NUTF2 PAPSS1 PBDC1 PHPT1 PPP1CA PPP1CB PPP1CC PRKAB2 PRPF31 PUF60 RFLNB RGMA SCNM1 SUV39H1 TFIP11 TLE5 TPP2 TRIP6 TSSK3 TTC23 TXNRD1 UNKL ZFYVE26 ZNF414
Entrez ID		29085	84988
HPRD ID		17849	16454
Ensembl ID		ENSG00000054148	ENSG00000160972
Uniprot IDs		Q9NRX4 V9HWC4	Q96I34
PDB IDs		2AI6 2HW4 2NMM 2OZW 2OZX
Enriched GO Terms of Interacting Partners?
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