GRINA and TIAL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GRINA	TIAL1
Description		glutamate ionotropic receptor NMDA type subunit associated protein 1	TIA1 cytotoxic granule associated RNA binding protein like 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane	Nucleus Nucleoplasm Cytoplasm Lysosome Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	Protein Binding Transmembrane Transporter Binding	DNA Binding RNA Binding MRNA 3'-UTR Binding MRNA 3'-UTR AU-rich Region Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Defense Response Germ Cell Development Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Posttranscriptional Gene Silencing Stem Cell Division Positive Regulation Of Hippo Signaling Positive Regulation Of Gene Silencing By MiRNA
Pathways			FGFR2 alternative splicing
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Fibrinogen levels ( 28107422) LDL cholesterol ( 25961943) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010)	Depressive symptoms (stressful life events interaction) ( 27529621) Monocyte percentage of white cells ( 32888494) Parkinson's disease ( 27182965) Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) ( 27047539)
Interacting Genes		9 interacting genes: DRD2 FMO1 GGT6 GLP1R GPX8 KRTAP19-5 KRTAP6-2 TIAL1 TMEM242	40 interacting genes: AKAP8L AOC1 BPIFA1 C10orf55 CAMK2A CELF4 CREBBP DAZAP2 FAM168A FAM168B FUBP1 GRINA INCA1 KLF1 KRTAP8-1 MAGED1 MAPK1 MAPK1IP1L MBNL2 MIR106A MIR106B MIR145 MIR199A1 MIR20A MIR29A MIR29C MIR34A MIR9-2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBPMS2 SMN1 SMN2 SNRPA VPS37C
Entrez ID		2907	7073
HPRD ID		15927	04563
Ensembl ID		ENSG00000178719	ENSG00000151923
Uniprot IDs		Q7Z429	Q01085 Q49AS9
PDB IDs			1X4G 2CQI 2DH7
Enriched GO Terms of Interacting Partners?
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