TIAL1 and CELF4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TIAL1	CELF4
Description		TIA1 cytotoxic granule associated RNA binding protein like 1	CUGBP Elav-like family member 4
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Lysosome Cytoplasmic Stress Granule Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Ribonucleoprotein Complex
	Molecular Function	DNA Binding RNA Binding MRNA 3'-UTR Binding MRNA 3'-UTR AU-rich Region Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Binding MRNA Binding Pre-mRNA Binding BRE Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Defense Response Germ Cell Development Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Posttranscriptional Gene Silencing Stem Cell Division Positive Regulation Of Hippo Signaling Positive Regulation Of Gene Silencing By MiRNA	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Splice Site Selection Germ Cell Development Embryo Development Ending In Birth Or Egg Hatching Negative Regulation Of Translation Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Excitatory Postsynaptic Potential Regulation Of Retina Development In Camera-type Eye
Pathways		FGFR2 alternative splicing
Drugs
Diseases
GWAS		Depressive symptoms (stressful life events interaction) ( 27529621) Monocyte percentage of white cells ( 32888494) Parkinson's disease ( 27182965) Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) ( 27047539)	Body fat mass ( 28552196) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Daytime nap ( 33568662) Depression ( 33859377) Educational attainment ( 25201988) Experiencing mood swings ( 29500382) Feeling fed-up ( 29500382) Feeling guilty ( 29500382) Feeling hurt ( 29500382) Feeling miserable ( 29500382) Gastroesophageal reflux disease ( 34187846) General factor of neuroticism ( 30867560) HDL cholesterol levels in HIV infection ( 33109212) Household income ( 31844048) Household income (MTAG) ( 31844048) Mood instability ( 31168069) Neurociticism ( 29500382) Neuroticism ( 27089181 27067015) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		40 interacting genes: AKAP8L AOC1 BPIFA1 C10orf55 CAMK2A CELF4 CREBBP DAZAP2 FAM168A FAM168B FUBP1 GRINA INCA1 KLF1 KRTAP8-1 MAGED1 MAPK1 MAPK1IP1L MBNL2 MIR106A MIR106B MIR145 MIR199A1 MIR20A MIR29A MIR29C MIR34A MIR9-2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBPMS2 SMN1 SMN2 SNRPA VPS37C	12 interacting genes: APP DSC2 LYST PCBP3 PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS2 SELENOS TIAL1
Entrez ID		7073	56853
HPRD ID		04563	12534
Ensembl ID		ENSG00000151923	ENSG00000101489
Uniprot IDs		Q01085 Q49AS9	Q9BZC1
PDB IDs		1X4G 2CQI 2DH7	2DGP 2DNK
Enriched GO Terms of Interacting Partners?
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