GRK5 and CABP1

Number of citations of the paper that reports this interaction (PubMedID 10625670)
127

Data Source:
BioGRID (pull down)

		GRK5	CABP1
Description		G protein-coupled receptor kinase 5	calcium binding protein 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Nuclear Speck Nuclear Membrane	Golgi Membrane Extracellular Space Cytoskeleton Plasma Membrane Cell Cortex Postsynaptic Density Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity G Protein-coupled Receptor Kinase Activity Protein Kinase C Binding Protein Binding ATP Binding Phospholipid Binding Beta-adrenergic Receptor Kinase Activity	Enzyme Inhibitor Activity Calcium Ion Binding Protein Binding Nuclear Localization Sequence Binding Calcium-dependent Protein Binding
	Biological Process	Protein Phosphorylation Apoptotic Process G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Tachykinin Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Regulation Of Signal Transduction Wnt Signaling Pathway Negative Regulation Of Apoptotic Process Protein Autophosphorylation Regulation Of Cell Cycle	Visual Perception Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Catalytic Activity Response To Stimulus
Pathways		G alpha (q) signalling events G alpha (s) signalling events	Sensory processing of sound by inner hair cells of the cochlea
Drugs
Diseases
GWAS		Coronary artery aneurysm in Kawasaki disease ( 27171184) Early onset periodontitis x smoking status interaction ( 31537151) Height ( 28552196) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean platelet volume ( 32888494 27863252) Methadone dose in opioid dependence ( 30060048) Neutrophil percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Risky sexual behaviors in alcohol dependence ( 28990359) Thrombin-induced platelet aggregation ( 32649856) Thymus and reactivation regulated chemokine levels ( 33227023) Type 2 diabetes ( 22961080) Venous thromboembolism ( 31420334 31676865) Waist circumference adjusted for body mass index ( 34021172)	C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809) Chronotype ( 30696823) Serum metabolite levels ( 33031748) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Systemic lupus erythematosus ( 33536424)
Interacting Genes		19 interacting genes: ADRB2 AGTR1 AVPR1A AVPR1B AVPR2 BDKRB2 CABP1 CALM1 CAV1 CHRM2 DLGAP2 GIT1 RCVRN RHO SNCA SNCB SNCG TACR1 TBXA2R	11 interacting genes: CACNA1A CACNA1C CSNK2A2 FOS GRK5 ITPR1 ITPR3 MPHOSPH9 NMT1 PPP3R1 SLC9A3R1
Entrez ID		2869	9478
HPRD ID		02926	12025
Ensembl ID		ENSG00000198873	ENSG00000157782
Uniprot IDs		P34947	Q9NZU7
PDB IDs		4TNB 4TND 6PJX	2K7B 2K7C 2K7D 2LAN 2LAP 3OX5 3OX6
Enriched GO Terms of Interacting Partners?
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