LAMA1 and FBLN2

Number of citations of the paper that reports this interaction (PubMedID 10934193)
49

Data Source:
HPRD (in vitro, in vivo)

		LAMA1	FBLN2
Description		laminin subunit alpha 1	fibulin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-1 Complex Laminin-3 Complex Extracellular Space Cell-cell Junction Membrane Extracellular Matrix Collagen-containing Extracellular Matrix	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Vesicle
	Molecular Function	Signaling Receptor Binding Extracellular Matrix Structural Constituent Protein Binding Protein C-terminus Binding Glycosphingolipid Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Protein Phosphorylation Cell Adhesion Cell Surface Receptor Signaling Pathway Axon Guidance Animal Organ Morphogenesis Tissue Development Regulation Of Cell Adhesion Regulation Of Cell Migration Camera-type Eye Development Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of Embryonic Development Blood Vessel Morphogenesis Epithelial Tube Branching Involved In Lung Morphogenesis Branching Involved In Salivary Gland Morphogenesis Retinal Blood Vessel Morphogenesis	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways		Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans L1CAM interactions MET activates PTK2 signaling	Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs		Lanoteplase
Diseases
GWAS		Adverse response to drug ( 30420678) Response to citalopram treatment ( 22760553) Type 2 diabetes ( 30054458 22693455 30297969 32499647)	Bipolar disorder with mood-incongruent psychosis ( 23092984) Body mass index ( 26426971) Hip circumference adjusted for BMI ( 34021172) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
Interacting Genes		20 interacting genes: ACHE APCS APP C3 COL7A1 DAG1 FBLN2 HSPG2 ITGA1 ITGA2 ITGB1 MEP1A NID1 NT5E PLAT PLG SAA1 SAA2 TMPRSS6 UBC	33 interacting genes: ACAN ATN1 BCAN COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL8A1 ELN ERCC6 FBN1 FBXW5 FN1 HOXA1 HSD3B7 HSPG2 ITGB3 JOSD1 LAMA1 LAMA5 LAMC2 LCE3D MRPS25 NID1 NUFIP2 OTX1 PRELP VCAN ZNF408 ZNF414
Entrez ID		284217	2199
HPRD ID		01033	00630
Ensembl ID		ENSG00000101680	ENSG00000163520
Uniprot IDs		P25391	P98095 Q86V58 Q9Y3V7
PDB IDs
Enriched GO Terms of Interacting Partners?
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