FBLN2 and BCAN

Number of citations of the paper that reports this interaction (PubMedID 11038354)
62

Data Source:
HPRD (in vitro)

		FBLN2	BCAN
Description		fibulin 2	brevican
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Vesicle	Extracellular Region Golgi Lumen Extracellular Matrix Anchored Component Of Membrane Lysosomal Lumen Glutamatergic Synapse
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding	Protein Binding Hyaluronic Acid Binding Carbohydrate Binding
	Biological Process	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization	Skeletal System Development Cell Adhesion Central Nervous System Development Hippocampus Development Synapse Maturation
Pathways		Molecules associated with elastic fibres Molecules associated with elastic fibres	Degradation of the extracellular matrix A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis Dermatan sulfate biosynthesis CS/DS degradation ECM proteoglycans Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective CHST14 causes EDS, musculocontractural type Defective CHSY1 causes TPBS Defective B3GALT6 causes EDSP2 and SEMDJL1
Drugs
Diseases
GWAS		Bipolar disorder with mood-incongruent psychosis ( 23092984) Body mass index ( 26426971) Hip circumference adjusted for BMI ( 34021172) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)	Blood protein levels ( 30072576 29875488)
Interacting Genes		33 interacting genes: ACAN ATN1 BCAN COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL8A1 ELN ERCC6 FBN1 FBXW5 FN1 HOXA1 HSD3B7 HSPG2 ITGB3 JOSD1 LAMA1 LAMA5 LAMC2 LCE3D MRPS25 NID1 NUFIP2 OTX1 PRELP VCAN ZNF408 ZNF414	10 interacting genes: ADAMTS4 FBLN2 MMP1 MMP10 MMP13 MMP2 MMP3 MMP7 MMP8 TNR
Entrez ID		2199	63827
HPRD ID		00630	02644
Ensembl ID		ENSG00000163520	ENSG00000132692
Uniprot IDs		P98095 Q86V58 Q9Y3V7	Q96GW7
PDB IDs
Enriched GO Terms of Interacting Partners?
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