GNAQ and CHRM3

  • Number of citations of the paper that reports this interaction (PubMedID 7629074)
  • 21
  • Data Source:
  • HPRD (in vivo)

GNAQ

CHRM3

Description G protein subunit alpha q cholinergic receptor muscarinic 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder ( 31043756)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Colorectal cancer ( 29228715)
  • Depression in smokers ( 30219690)
  • Electroencephalogram traits ( 25387704)
  • Feeling worry ( 29500382)
  • FEV1 ( 30804560)
  • Generalized epilepsy ( 22949513)
  • Gut microbiota beta diversity (weighted UniFrac distance) ( 33208821)
  • Hallucinations in long-term cannabis use ( 31740666)
  • Hypertension ( 17554300)
  • Interleukin-6 (red blood cell fatty acid level interaction) ( 28820441)
  • Lung function (FEV1/FVC) ( 28166213 30804560)
  • Peak expiratory flow ( 30804560)
  • Platelet count ( 21507922)
  • Post bronchodilator FEV1 ( 26634245)
  • Reflection (response to stress) ( 30886212)
  • Sulfasalazine-induced agranulocytosis ( 28762467)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes 48 interacting genes: ADHFE1 ADRA1B AIP AKAP13 BDKRB1 BTK CCR5 CHRM3 CRHR1 CYTH1 CYTH2 FFAR1 FFAR2 GALR2 GRK2 GRM2 GRM4 GRM7 HTR2A HTR2B HTR2C HTR6 KDR LUM MRGPRX1 NT5C3A PIK3CA PLCB1 PLCB2 PPT1 PTGIR RGS13 RGS16 RGS18 RGS2 RGS4 RGS5 RGS7 RIC8A RIC8B S1PR2 S1PR3 SLC9A3R1 TBXA2R TSHR TTC1 TUB VIPR1 26 interacting genes: ARF1 ARF6 BSG CALM3 CCDC184 CD2BP2 COMMD7 CSNK1A1 GNAQ GNAS GPRASP1 GRK6 GZMB JAKMIP1 MAGED2 PDGFRB POM121C PPP1R9B RAB5IF RGS7 SEPTIN3 SET SGSM3 TAP1 TPM3 YIPF3
Entrez ID 2776 1131
HPRD ID 02998 00329
Ensembl ID ENSG00000156052 ENSG00000133019
Uniprot IDs A0A024R240 P50148 A0A024R3W1 P20309
PDB IDs 6VU5 2CSA
Enriched GO Terms of Interacting Partners?
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