RNF115 and ZNRD2

Number of citations of the paper that reports this interaction (PubMedID 11591653)
42

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		RNF115	ZNRD2
Description		ring finger protein 115	zinc ribbon domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination	Mitotic Cell Cycle Cell Division
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Breast cancer ( 25751625 29059683) HDL cholesterol levels ( 32203549) Platelet distribution width ( 32888494)	Glaucoma (primary open-angle) ( 33627673)
Interacting Genes		35 interacting genes: AKT1 APP ATN1 CD160 CDK10 CST3 DAZAP2 DOCK4 EGFR FOLR3 HRAS IGHA1 MAVS MDM4 MFAP4 NFKBIA RAB7A RAD23A RPL18A STING1 TTR UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2N UBE2W USP9X VCP ZNRD2	27 interacting genes: ACTN2 C2CD6 CCDC33 CCNH CCT2 CCT3 CCT5 CCT7 FNDC11 FXR2 IL16 INCA1 MYO15B NME6 NOC4L PIAS2 POLA2 RNF115 RNF4 SNAPC5 STAT3 SUMO1P1 TRAF3IP3 TRAPPC6A UBE2I VTA1 ZMYM5
Entrez ID		27246	10534
HPRD ID		18328	06921
Ensembl ID		ENSG00000265491	ENSG00000173465
Uniprot IDs		Q9Y4L5	G3V1B8 O60232
PDB IDs			6HCZ
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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