UTP25 and TRIM62

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UTP25	TRIM62
Description		UTP25 small subunit processor component	tripartite motif containing 62
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Small-subunit Processome	Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding RRNA Binding U3 SnoRNA Binding	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Protein Catabolic Process Protein Destabilization Positive Regulation Of Embryonic Development Embryonic Organ Development Protein Localization To Nucleolus	Negative Regulation Of Epithelial To Mesenchymal Transition Protein Ubiquitination Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein K27-linked Ubiquitination Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Viral Release From Host Cell Positive Regulation Of Antifungal Innate Immune Response
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	Interferon gamma signaling
Drugs
Diseases
GWAS			Gut microbiota (beta diversity) ( 27723756)
Interacting Genes		11 interacting genes: AP2M1 APP CEP70 MAGEA11 MEOX2 MID2 MIPOL1 RUFY1 TRIM62 TRIM9 ZBTB10	19 interacting genes: CARD9 EAF1 EPN2 EXOSC5 FAIM GLRX PPP1R18 SKIL SMAD2 SP7 TBC1D7 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2L6 UBXN7 UTP25
Entrez ID		27042	55223
HPRD ID		14535	07697
Ensembl ID		ENSG00000117597	ENSG00000116525
Uniprot IDs		Q68CQ4	Q9BVG3
PDB IDs
Enriched GO Terms of Interacting Partners?
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