UTP25 and TRIM9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UTP25	TRIM9
Description		UTP25 small subunit processor component	tripartite motif containing 9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Small-subunit Processome	Cytoplasm Cytoskeleton Synaptic Vesicle Dendrite
	Molecular Function	RNA Binding Protein Binding RRNA Binding U3 SnoRNA Binding	Protein Binding Zinc Ion Binding Protein Domain Specific Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Protein Catabolic Process Protein Destabilization Positive Regulation Of Embryonic Development Embryonic Organ Development Protein Localization To Nucleolus	Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Psychosis (atypical) ( 24132900) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		11 interacting genes: AP2M1 APP CEP70 MAGEA11 MEOX2 MID2 MIPOL1 RUFY1 TRIM62 TRIM9 ZBTB10	33 interacting genes: AP3M1 BTRC CHFR CSNK1D CWF19L2 DNAAF2 DTNBP1 DTX3L EVL FAM124B FAM90A1 GFM2 LONRF1 MDM2 MNAT1 MUL1 NCF1 NFKBID NTAQ1 PCGF3 RNF166 RPL4P5 SHANK3 SNAP25 SPG21 TRIM27 TRIM46 TRIM8 TSSK3 USP2 USP21 UTP25 VASP
Entrez ID		27042	114088
HPRD ID		14535	05947
Ensembl ID		ENSG00000117597	ENSG00000100505
Uniprot IDs		Q68CQ4	Q9C026
PDB IDs			2DB8 7B2S
Enriched GO Terms of Interacting Partners?
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