USP21 and HOXC10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		USP21	HOXC10
Description		ubiquitin specific peptidase 21	homeobox C10
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane	Chromatin Nucleus Nucleoplasm Nuclear Body
	Molecular Function	Transcription Coactivator Activity Thiol-dependent Deubiquitinase Protein Binding Cysteine-type Peptidase Activity NEDD8-specific Protease Activity Metal Ion Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Histone Deubiquitination Protein Deubiquitination Neuron Projection Development Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cold-induced Thermogenesis
Pathways		TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway Ub-specific processing proteases
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		61 interacting genes: ADAMTSL4 ATXN3 AURKA BAP1 BRCA2 CBL CBLC CDC34 CPSF6 DTX3 EFEMP2 ESPL1 EXOSC10 FOXM1 H2AC18 HOXC10 ISG15 JOSD1 KCTD9 KRT40 LRSAM1 MAPK3 MPP1 NANOG OTUB1 OTUB2 PCGF6 RBCK1 RNF144A RNF185 SENP3 SENP8 SLF1 STAMBP SYNE1 TP53 TRAF6 TRIM23 TRIM5 TRIM54 TRIM63 TRIM8 TRIM9 UBC UBE2D1 UBE2S UCHL1 UCHL3 USP14 USP15 USP2 USP20 USP28 USP33 USP4 USP51 USP7 USP8 WDR47 YOD1 ZNF350	7 interacting genes: CDC27 CYP27B1 EGFR ELOB NUP205 USP21 YWHAG
Entrez ID		27005	3226
HPRD ID		05291	05710
Ensembl ID		ENSG00000143258	ENSG00000180818
Uniprot IDs		Q9UK80	Q53XI4 Q9NYD6
PDB IDs		2Y5B 3I3T 3MTN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?