TIPRL and PPP6C

Number of citations of the paper that reports this interaction (PubMedID 24255178)
195

Data Source:
BioGRID (affinity chromatography technology, pull down, affinity chromatography technology)

		TIPRL	PPP6C
Description		TOR signaling pathway regulator	protein phosphatase 6 catalytic subunit
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding	Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	DNA Damage Checkpoint Signaling TOR Signaling Negative Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Phosphoprotein Phosphatase Activity	G1/S Transition Of Mitotic Cell Cycle Protein Dephosphorylation Innate Immune Response COPII Vesicle Coating
Pathways			Telomere Extension By Telomerase COPII-mediated vesicle transport
Drugs
Diseases
GWAS		LDL cholesterol levels in HIV infection ( 33109212) Red cell distribution width ( 32888494)	Pulse pressure ( 27841878) Refractive error ( 32231278) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		5 interacting genes: APP PPP2CB PPP4C PPP6C UFL1	7 interacting genes: IGBP1 NFKBIE PRKDC TGFBR1 TIPRL VAC14 ZNRF2
Entrez ID		261726	5537
HPRD ID		14608	02141
Ensembl ID		ENSG00000143155	ENSG00000119414
Uniprot IDs		O75663	A0A024R861 O00743
PDB IDs		5D9G
Enriched GO Terms of Interacting Partners?
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