PPP6C and ZNRF2

Number of citations of the paper that reports this interaction (PubMedID 27244671)
5

Data Source:
BioGRID (affinity chromatography technology, enzymatic study)

		PPP6C	ZNRF2
Description		protein phosphatase 6 catalytic subunit	zinc and ring finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol	Fibrillar Center Nucleoplasm Cytoplasm Lysosomal Membrane Cytosol Plasma Membrane Endosome Membrane Cytoplasmic Vesicle Membrane Protein-containing Complex Presynaptic Membrane Cell Projection Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Dephosphorylation Innate Immune Response COPII Vesicle Coating	Protein Ubiquitination
Pathways		Telomere Extension By Telomerase COPII-mediated vesicle transport	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Pulse pressure ( 27841878) Refractive error ( 32231278) Systolic blood pressure ( 27841878 30578418)	Cadmium levels ( 26025379)
Interacting Genes		7 interacting genes: IGBP1 NFKBIE PRKDC TGFBR1 TIPRL VAC14 ZNRF2	16 interacting genes: AKTIP ATP1A1 MTOR PPP6C UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2T UBE2V1 UBE2W
Entrez ID		5537	223082
HPRD ID		02141	15894
Ensembl ID		ENSG00000119414	ENSG00000180233
Uniprot IDs		A0A024R861 O00743	A0A090N8Y8 Q8NHG8
PDB IDs
Enriched GO Terms of Interacting Partners?
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