GGA1 and LRP3

Number of citations of the paper that reports this interaction (PubMedID 11390366)
50

Data Source:
HPRD (two hybrid, in vitro)

		GGA1	LRP3
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 1	LDL receptor related protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Early Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle	Plasma Membrane Clathrin-coated Pit Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding Small GTPase Binding Phosphatidylinositol Binding Ubiquitin Binding
	Biological Process	Intracellular Protein Transport Protein Localization Protein Localization To Cell Surface Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Positive Regulation Of Protein Catabolic Process Toxin Transport Protein Localization To Ciliary Membrane	Receptor-mediated Endocytosis Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Osteoblast Differentiation Transport Across Blood-brain Barrier
Pathways		TBC/RABGAPs Amyloid fiber formation
Drugs
Diseases
GWAS		Health literacy ( 31250787)	Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433)
Interacting Genes		41 interacting genes: ADRA2B AFTPH AP1AR APP ARF1 ARF3 ARF5 ATXN7L1 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CLINT1 CLTC CSNK2A1 DGCR6L DTNB EGFR F8 GGA2 GGA3 IGF2R ING5 LRP3 M6PR RABEP1 RABGEF1 RNF11 RPS27A SCARB1 SMAD3 SORL1 SORT1 STAB1 SYNRG TOLLIP TSG101 UBC VPS18	3 interacting genes: GGA1 GGA2 MTNR1A
Entrez ID		26088	4037
HPRD ID		12078	04406
Ensembl ID		ENSG00000100083	ENSG00000130881
Uniprot IDs		Q9UJY5	O75074
PDB IDs		1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W
Enriched GO Terms of Interacting Partners?
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