GGA1 and GGA2

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, pull down, pull down)

		GGA1	GGA2
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 1	golgi associated, gamma adaptin ear containing, ARF binding protein 2
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GO Annotations	Cellular Component	Nucleoplasm Early Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin-coated Vesicle Early Endosome Membrane
	Molecular Function	Molecular_function Protein Binding Small GTPase Binding Phosphatidylinositol Binding Ubiquitin Binding	Protein Binding Small GTPase Binding Phosphatidylinositol Binding Ubiquitin Binding
	Biological Process	Intracellular Protein Transport Protein Localization Protein Localization To Cell Surface Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Positive Regulation Of Protein Catabolic Process Toxin Transport Protein Localization To Ciliary Membrane	Intracellular Protein Transport Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport
Pathways		TBC/RABGAPs Amyloid fiber formation	TBC/RABGAPs Amyloid fiber formation
Drugs
Diseases
GWAS		Health literacy ( 31250787)
Interacting Genes		41 interacting genes: ADRA2B AFTPH AP1AR APP ARF1 ARF3 ARF5 ATXN7L1 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CLINT1 CLTC CSNK2A1 DGCR6L DTNB EGFR F8 GGA2 GGA3 IGF2R ING5 LRP3 M6PR RABEP1 RABGEF1 RNF11 RPS27A SCARB1 SMAD3 SORL1 SORT1 STAB1 SYNRG TOLLIP TSG101 UBC VPS18	36 interacting genes: ADRA2B AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC FBXO7 GGA1 GGA3 GOLGA2 HGS HTT IGF2R LRP3 M6PR MAP3K1 MEMO1 PIN1 RABEP1 RABGEF1 RNF11 RTN4IP1 SORL1 SORT1 SPG21 STAB1 SYNRG TOLLIP TRIM23 VPS18
Entrez ID		26088	23062
HPRD ID		12078	09347
Ensembl ID		ENSG00000100083	ENSG00000103365
Uniprot IDs		Q9UJY5	Q9UJY4
PDB IDs		1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W	1MHQ
Enriched GO Terms of Interacting Partners?
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