APPL1 and DPYSL5

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

APPL1

DPYSL5

Description adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 dihydropyrimidinase like 5
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cortical surface area (min-P) ( 32665545)
  • Cortical surface area (MOSTest) ( 32665545)
  • Cortical thickness (MOSTest) ( 32665545)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Fasting blood glucose ( 22581228)
  • Fasting blood glucose (BMI interaction) ( 22581228)
  • Fasting glucose ( 34059833)
  • Fasting insulin ( 34059833)
  • Obesity-related traits ( 23251661)
  • Reflection (response to stress) ( 30886212)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Urate levels ( 31578528)
  • Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
  • White blood cell count ( 32888494)
Interacting Genes 65 interacting genes: ADI1 ADIPOR1 ADIPOR2 AGL AKT1 AKT2 ANKRD1 APPL2 ATP2A1 BATF3 BIN1 BRWD1 C1QTNF9 CBL CBLB CIPC CMTM4 CTTNBP2 DACT1 DCC DNM2 DOK2 DOK3 DOK7 DPYSL5 DTNA DYSF EGFR FARS2 FSHR GPC3 HDAC2 HSPB1 ID1 IMPDH2 INO80E KLF15 KXD1 LUC7L MAGEA9 MAGEC3 MAP3K1 MEOX1 MTA2 MYCBP2 MYH3 PIK3CA PIK3R1 PIK3R2 PLEKHF2 PNMA5 RAB21 RAB5A RBBP7 RHEBL1 RUVBL2 SCAPER SH2D2A SOCS6 SPART TP53 TP53BP2 TRAF2 UBE2O ZNF829 10 interacting genes: APPL1 CFAP161 DARS2 DPYS DPYSL2 DPYSL3 DPYSL4 FBN2 FES HSPA5
Entrez ID 26060 56896
HPRD ID 05053 10522
Ensembl ID ENSG00000157500 ENSG00000157851
Uniprot IDs Q9UKG1 Q9BPU6
PDB IDs 2EJ8 2ELA 2ELB 2Q12 2Q13 2Z0N 2Z0O 5C5B 4B90 4B91 4B92
Enriched GO Terms of Interacting Partners?
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