APPL1 and PIK3R2

  • Number of citations of the paper that reports this interaction (PubMedID 25814554)
  • 26
  • Data Source:
  • BioGRID (two hybrid)

APPL1

PIK3R2

Description adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 phosphoinositide-3-kinase regulatory subunit 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Basophil count ( 32888494)
  • Basophil percentage of white cells ( 32888494)
  • Mental health study participation (completed survey) ( 31263887)
Interacting Genes 65 interacting genes: ADI1 ADIPOR1 ADIPOR2 AGL AKT1 AKT2 ANKRD1 APPL2 ATP2A1 BATF3 BIN1 BRWD1 C1QTNF9 CBL CBLB CIPC CMTM4 CTTNBP2 DACT1 DCC DNM2 DOK2 DOK3 DOK7 DPYSL5 DTNA DYSF EGFR FARS2 FSHR GPC3 HDAC2 HSPB1 ID1 IMPDH2 INO80E KLF15 KXD1 LUC7L MAGEA9 MAGEC3 MAP3K1 MEOX1 MTA2 MYCBP2 MYH3 PIK3CA PIK3R1 PIK3R2 PLEKHF2 PNMA5 RAB21 RAB5A RBBP7 RHEBL1 RUVBL2 SCAPER SH2D2A SOCS6 SPART TP53 TP53BP2 TRAF2 UBE2O ZNF829 59 interacting genes: APP APPL1 AR ARRB1 AXL CBL CD28 CRK CRKL CSF1R DYDC1 EGF EGFR ENKUR EPHA2 ERBB2 ERBB3 ERBB4 FBXL2 FGFR1 FYN GAB1 GHR GOLGA2 GRB2 GRN HCK IGF1R IKZF3 IRS1 IRS2 KIT KRAS KRT15 KRT20 KRT38 LAMB2 LMNA LTBP3 MET MRFAP1L1 PDGFRB PIK3CD RINT1 SEPTIN2 SHC1 SOCS1 SOCS6 SOCS7 SOS1 STAB1 STAT3 SYK TEC TGFBR1 TGFBR2 TRIM23 WASF3 YWHAB
Entrez ID 26060 5296
HPRD ID 05053 04404
Ensembl ID ENSG00000157500 ENSG00000105647
Uniprot IDs Q9UKG1 O00459
PDB IDs 2EJ8 2ELA 2ELB 2Q12 2Q13 2Z0N 2Z0O 5C5B 2KT1 2XS6 3MTT 3O5Z 6OX7 6U28
Enriched GO Terms of Interacting Partners?
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