GAP43 and PLCD1

Number of citations of the paper that reports this interaction (PubMedID 12805215)
7

Data Source:
HPRD (in vivo)

		GAP43	PLCD1
Description		growth associated protein 43	phospholipase C delta 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Postsynaptic Density Dendrite Filopodium Membrane Growth Cone Membrane Perikaryon GABA-ergic Synapse	Cytoplasm Plasma Membrane Extracellular Exosome
	Molecular Function	Phosphatidylserine Binding Protein Binding Calmodulin Binding Lysophosphatidic Acid Binding Phosphatidylinositol Phosphate Binding	Phosphatidylinositol Phospholipase C Activity Calcium Ion Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding GTPase Activating Protein Binding
	Biological Process	Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Response To Wounding Glial Cell Differentiation Axon Choice Point Recognition Axon Regeneration Regulation Of Growth Tissue Regeneration Cell Fate Commitment Regulation Of Filopodium Assembly Regulation Of Postsynaptic Specialization Assembly	Phospholipid Metabolic Process Lipid Catabolic Process Phosphatidylinositol Metabolic Process Phosphatidylinositol-mediated Signaling
Pathways		L1CAM interactions	Synthesis of IP3 and IP4 in the cytosol
Drugs			1D-myo-inositol 1,4,5-trisphosphate Inositol 2,4,5-trisphosphate
Diseases
GWAS		Borderline personality disorder ( 28632202) Breast size ( 22747683) Eye color ( 33692100) Metabolite levels ( 23823483) Proliferative diabetic retinopathy ( 31482010) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Seasonality and depression ( 30217971) Urate levels in obese individuals ( 25811787)
Interacting Genes		10 interacting genes: CALM1 CD47 CSNK2A1 ELAVL4 LOX PLCD1 PRKCB PRKCD RABEP1 SPTAN1	11 interacting genes: APP CALM1 GAP43 HGS KPNB1 NTAQ1 PAXIP1 RALA RALB TGM2 USP54
Entrez ID		2596	5333
HPRD ID		01198	09073
Ensembl ID		ENSG00000172020	ENSG00000187091
Uniprot IDs		P17677 Q5U058	A0A384MR47 A8K8F9 P51178
PDB IDs
Enriched GO Terms of Interacting Partners?
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