KANK2 and GRB10

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

KANK2

GRB10

Description KN motif and ankyrin repeat domains 2 growth factor receptor bound protein 10
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 23512250)
  • Area under the curve of insulin levels ( 24699409)
  • Birth weight ( 31043758)
  • Blood pressure (smoking interaction) ( 25189868)
  • Body mass index ( 26426971)
  • Body mass index (age <50) ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Brain morphology (MOSTest) ( 32665545)
  • Chronotype ( 30696823)
  • Corpus callosum mid-anterior volume ( 31530798)
  • Corrected insulin response ( 24699409)
  • Corrected insulin response adjusted for insulin sensitivity index ( 24699409)
  • Diastolic blood pressure ( 30224653)
  • Eosinophil counts ( 32888494 27863252)
  • Estimated glomerular filtration rate ( 31152163 31015462)
  • Fasting blood glucose ( 22581228)
  • Fasting blood glucose (BMI interaction) ( 22581228)
  • Fasting glucose ( 33402679 34059833)
  • Fasting insulin ( 34059833)
  • Femoral neck bone mineral density ( 22504420)
  • Fractures ( 30158200)
  • Heel bone mineral density ( 30598549)
  • Hip circumference adjusted for BMI ( 34021172)
  • Incremental insulin ( 24699409)
  • Insulin levels adjusted for BMI ( 24699409)
  • Insulin-related traits (multivariate analysis) ( 32002517)
  • Mean corpuscular volume ( 32888494)
  • Mean reticulocyte volume ( 32888494)
  • Metabolite levels ( 23823483)
  • Morning person ( 30696823)
  • Ratio of the area under the curve for insulin and the area under the curve for glucose ( 24699409)
  • Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901)
  • Schizophrenia (treatment resistant) ( 25223841)
  • Subcortical volume (MOSTest) ( 32665545)
  • Sum eosinophil basophil counts ( 27863252)
  • Systemic sclerosis ( 21779181)
  • Total body bone mineral density ( 29304378)
  • Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes 185 interacting genes: ABI3 AEN ANKRD11 AP2B1 ARL14EP ASB15 BEND7 BIRC7 BLZF1 BORCS6 C11orf1 C2orf68 CADPS CAMK2G CAPN3 CARD10 CARD9 CBX8 CCDC33 CCDC57 CCDC88B CDC20B CDC5L CDKL3 CEACAM6 CEP55 CEP63 CEP70 CHCHD3 CHIC2 CINP COG6 CRX CSNK2A1 CUTC CWF19L2 CYTH4 DDIT4L DLGAP3 DPEP2NB DTX2 DYNLL1 DYNLL2 EFHC2 EIF4E ELOA EXOSC8 FAM161A FAM90A1 FHL2 FHL3 FKBP6 GADD45GIP1 GATA1 GEMIN4 GKAP1 GMCL1 GMNN GOLGA2 GOLGA6A GOLGA6L9 GPANK1 GPKOW GPSM1 GRB10 HAND2 HOMER3 HSF2BP HSPB2 HSPB2-C11orf52 IHO1 IKZF3 IL16 KIF9 KIFAP3 KIFC3 KRT27 KRT34 KRT40 KRT75 KRT86 KRTAP6-3 L3MBTL3 LBX1 LENG1 LHX1 LHX3 LMO1 LMO2 LMO3 LMO4 LZTS1 MAGEB4 MCCD1 MCRS1 MED19 MEOX1 MEOX2 MID2 MITD1 MKRN3 MOB1A MOB3C MORN3 MSS51 MTUS2 MYOZ3 NCOA1 NCOA5 NECAB2 NOS3 NUTM1 OIP5 PAX6 PCBD1 PDE9A PDLIM7 PFDN6 PIBF1 PLAGL2 PLEKHA2 PNKP PPP1CB PRDM14 PRDM6 PRKAR1B PRMT5 PRPF18 PRPF31 PRR5L PSEN1 PSMB4 PSTPIP1 RAB11FIP2 RALBP1 RBCK1 RHOH SCARA5 SCNM1 SERTAD3 SNAPIN SNW1 SORBS3 SRPK2 STAC SYT6 TAX1BP1 TEX11 TFIP11 TGM5 THAP1 THAP6 TIFA TLE5 TOP3B TRAF1 TRAF2 TRAF4 TRIB3 TRIM35 TRIM54 TSGA10 TSGA10IP TSPYL6 TXLNA UBAP2 USHBP1 UTP14C VMAC VPS52 VWC2 WASF3 WASHC1 ZBTB42 ZFP57 ZMAT2 ZMYND12 ZNF212 ZNF414 ZNF512 ZNF648 ZNF774 ZNF784 ZNHIT1 ZRANB1 48 interacting genes: AANAT ABL1 AKT1 APP BAIAP2 BCR BLK CHFR CNOT9 DOK1 EGFR ELK1 EPHB1 ERBB2 ERBB4 FARS2 FYN GHR GIGYF1 GIGYF2 IGF1R INSR IRS1 JAK2 KANK2 KDR KIT KPNA3 MAP2K1 MAP3K14 MAPK1 MEGF10 NEDD4 NFKBID NOA1 PDGFRB PICK1 RAF1 RET SRC TEKT4 TEPSIN TNK1 TRIM55 TRIM63 TXK ZDHHC17 ZMYND19
Entrez ID 25959 2887
HPRD ID 12463 03312
Ensembl ID ENSG00000197256 ENSG00000106070
Uniprot IDs Q63ZY3 Q13322
PDB IDs 4HBD 5YBV 6TMD 1NRV 3HK0
Enriched GO Terms of Interacting Partners?
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