RNF19A and C11orf58

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		RNF19A	C11orf58
Description		ring finger protein 19A, RBR E3 ubiquitin protein ligase	chromosome 11 open reading frame 58
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Centrosome Cytosol Integral Component Of Membrane Hippocampal Mossy Fiber To CA3 Synapse Postsynapse Glutamatergic Synapse	Cellular_component
	Molecular Function	Protein Binding Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Molecular_function
	Biological Process	Protein Polyubiquitination Microtubule Cytoskeleton Organization Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission	Biological_process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Atrioventricular conduction ( 21041692) Recurrent major depressive disorder ( 29317602)	Chronotype ( 30696823) Coronary artery disease ( 33020668) Femoral neck bone mineral density ( 29499414) Heel bone mineral density ( 30598549 28869591) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Lumbar spine bone mineral density ( 29499414) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		17 interacting genes: C11orf58 CASR ILK MAP3K20 MAP3K7 NUDT21 RPS6KA5 SNCAIP SOD1 SUFU TUBG1 TUBG2 UBE2D2 UBE2E2 UBE2L3 UBE2L6 VCP	16 interacting genes: A2M CEP126 EEF1G FBN3 MBTPS1 POLR2C PTN RNF19A RPLP1 SEMA5B SF3B1 SHC1 SLC44A1 SNCAIP TRA2A ZBTB48
Entrez ID		25897	10944
HPRD ID		06176	18069
Ensembl ID		ENSG00000034677	ENSG00000110696
Uniprot IDs		Q9NV58	O00193
PDB IDs
Enriched GO Terms of Interacting Partners?
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