C11orf58 and FBN3

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		C11orf58	FBN3
Description		chromosome 11 open reading frame 58	fibrillin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Molecular_function	Extracellular Matrix Structural Constituent Calcium Ion Binding
	Biological Process	Biological_process	Anatomical Structure Morphogenesis
Pathways			Degradation of the extracellular matrix Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Chronotype ( 30696823) Coronary artery disease ( 33020668) Femoral neck bone mineral density ( 29499414) Heel bone mineral density ( 30598549 28869591) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Lumbar spine bone mineral density ( 29499414) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494) Serum alkaline phosphatase levels ( 33547301)	Attention deficit hyperactivity disorder ( 30563984) Blood protein levels ( 28240269) Macular telangiectasia type 2 ( 33654266) Neurocognitive impairment in HIV-1 infection (continuous) ( 28447399) Pre-treatment viral load in HIV-1 infection ( 31219150) Refractive error ( 32231278) Serum metabolite levels ( 33031748) Serum metabolite ratios in chronic kidney disease ( 29545352)
Interacting Genes		16 interacting genes: A2M CEP126 EEF1G FBN3 MBTPS1 POLR2C PTN RNF19A RPLP1 SEMA5B SF3B1 SHC1 SLC44A1 SNCAIP TRA2A ZBTB48	13 interacting genes: ANXA7 BID C11orf58 CDKN1A DAZAP2 GADD45A GSK3B NUDT21 PIK3R3 RPN2 RPS6KA6 TK1 TSC22D1
Entrez ID		10944	84467
HPRD ID		18069	10538
Ensembl ID		ENSG00000110696	ENSG00000142449
Uniprot IDs		O00193	A0A494C0D8 A8KAY2 Q75N90
PDB IDs
Enriched GO Terms of Interacting Partners?
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