ASF1A and VPS28

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		ASF1A	VPS28
Description		anti-silencing function 1A histone chaperone	VPS28 subunit of ESCRT-I
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Protein-containing Complex	ESCRT I Complex Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Extracellular Exosome
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Protein Binding Ubiquitin Binding Protein-containing Complex Binding
	Biological Process	Osteoblast Differentiation DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Muscle Cell Differentiation	Macroautophagy Negative Regulation Of Protein Ubiquitination Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Endocytosis
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF)	Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494) Multiple sclerosis ( 31604244) QT interval ( 19305408)	Blood metabolite levels ( 26401656) Educational attainment ( 25201988)
Interacting Genes		33 interacting genes: ASF1B CHAF1A CHAF1B CHEK2 H3-3A H3-4 H3C3 H3C6 H4-16 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HIRA HTATIP2 MCM2 PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17	46 interacting genes: ABI2 ASF1A BEX2 BLZF1 CACNA1I CARD9 CBX5 CCDC146 CDK18 CEP57L1 COX5B FABP3 GABARAP GEM GLCCI1 GOLGA2 INCA1 LMO3 MBIP NRDE2 NXF1 PDCD6IP PNMA5 PRKAA2 PRKAB2 RASSF5 SAXO1 SHC3 SKIL SMN1 SMN2 SUOX TCF12 TCF4 TRIM27 TRIM54 TSG101 TSNAX UBA52 UBC USHBP1 USP2 VPS37A VPS37B VPS37C VPS52
Entrez ID		25842	51160
HPRD ID		16459	11675
Ensembl ID		ENSG00000111875	ENSG00000160948
Uniprot IDs		Q9Y294	A0A0S2Z5H5 Q548N1 Q9UK41
PDB IDs		1TEY 2I32 2IIJ 2IO5 3AAD 5C3I 6F0F 6F0G 6F0H	6VME
Enriched GO Terms of Interacting Partners?
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