FSHR and TOP1

  • Number of citations of the paper that reports this interaction (PubMedID 15196694)
  • 17

FSHR

TOP1

Description follicle stimulating hormone receptor DNA topoisomerase I
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide) ( 23648065)
  • Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877)
  • Cerebrospinal fluid t-tau levels in normal cognition ( 29274321)
  • Chronotype ( 30696823)
  • Daytime nap ( 33568662)
  • Depressive symptoms (SSRI exposure interaction) ( 25649181)
  • Erectile dysfunction and prostate cancer treatment ( 20932654)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • Laterality in neovascular age-related macular degeneration ( 28775256)
  • Lean body mass ( 28552196)
  • Low density lipoprotein cholesterol levels ( 30498476)
  • Lung cancer in ever smokers ( 28604730)
  • Metabolite levels ( 23823483)
  • Morning person ( 30696823)
  • Plasma anti-thyroglobulin levels ( 29678681)
  • Polycystic ovary syndrome ( 22885925 21151128)
  • Radiation response ( 20923822)
  • Recurrent major depressive disorder ( 34099189)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
  • Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309)
  • Antipsychotic drug-induced weight gain in schizophrenia ( 31447353)
  • Brain morphology (MOSTest) ( 32665545)
  • Cholesterol, total ( 24097068 20686565)
  • Fasting glucose ( 33402679)
  • Hemoglobin ( 32888494)
  • Hip circumference adjusted for BMI ( 34021172)
  • LDL cholesterol ( 24097068 20686565)
  • LDL cholesterol levels ( 28334899)
  • LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Male-pattern baldness ( 28196072)
  • Metabolite levels ( 23823483)
  • PR interval ( 32439900)
  • Red blood cell count ( 32888494)
  • Refractive error ( 32231278)
  • Total cholesterol levels ( 28334899)
  • Urate levels ( 31578528)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 20 interacting genes: AKT2 APPL1 ARR3 CANX CBX5 CGA FSHB GRK2 GRK4 GRK6 MT-RNR2 RPS27A S100A10 TOP1 TUG1 UBA52 UBB UBC YWHAQ ZBTB16 61 interacting genes: APAF1 APP ATM BARD1 BRCA1 BRD2 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PIAS4 PPP2R2B PRB1 PRKDC PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRPK2 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I XRCC5 XRCC6
Entrez ID 2492 7150
HPRD ID 00639 00535
Ensembl ID ENSG00000170820 ENSG00000198900
Uniprot IDs A0A1D5RMN4 P23945 P11387 Q9BVT2
PDB IDs 1XUN 1XWD 4AY9 4MQW 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8
Enriched GO Terms of Interacting Partners?
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