PLXNB2 and CENPU

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		PLXNB2	CENPU
Description		plexin B2	centromere protein U
Image			No pdb structure
GO Annotations	Cellular Component	Semaphorin Receptor Complex Integral Component Of Plasma Membrane Cell Surface Extracellular Exosome	Kinetochore Nucleus Nucleoplasm Cytosol Centriolar Satellite
	Molecular Function	Protein Binding Semaphorin Receptor Activity	Protein Binding
	Biological Process	Neural Tube Closure Regulation Of Protein Phosphorylation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Cell Adhesion Neuroblast Proliferation Brain Development Regulation Of Cell Shape Positive Regulation Of Neuron Projection Development Regulation Of Cell Migration Regulation Of GTPase Activity Positive Regulation Of Translation Positive Regulation Of Axonogenesis Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance Excitatory Synapse Assembly Regulation Of Neuron Migration	Chordate Embryonic Development
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576 29875488) Cutaneous malignant melanoma ( 32341527) Cutaneous melanoma or hair colour ( 32341527) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte counts ( 32888494) Nevus count or cutaneous melanoma ( 32341527) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sensorimotor dexterity ( 31596458) Systolic blood pressure ( 30224653)
Interacting Genes		7 interacting genes: ARHGEF11 ARHGEF12 CENPU HMOX2 PFDN1 PTN RND1	18 interacting genes: E2F6 EIF4G1 GIT1 LAMC1 MLF1 NDUFS2 NUP62 OGT PGRMC1 PLK2 PLK3 PLXNB2 ROBO2 SPTBN4 TFIP11 TUBB2B UPF2 XRCC6
Entrez ID		23654	79682
HPRD ID		05050	14722
Ensembl ID		ENSG00000196576	ENSG00000151725
Uniprot IDs		O15031	Q71F23
PDB IDs		4E71
Enriched GO Terms of Interacting Partners?
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