PLXNB2 and RND1

Number of citations of the paper that reports this interaction (PubMedID 12730235)
43

Data Source:
HPRD (two hybrid)

		PLXNB2	RND1
Description		plexin B2	Rho family GTPase 1
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GO Annotations	Cellular Component	Semaphorin Receptor Complex Integral Component Of Plasma Membrane Cell Surface Extracellular Exosome	Cytoskeleton Plasma Membrane Adherens Junction Cell Cortex Actin Cytoskeleton Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Semaphorin Receptor Activity	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Neural Tube Closure Regulation Of Protein Phosphorylation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Cell Adhesion Neuroblast Proliferation Brain Development Regulation Of Cell Shape Positive Regulation Of Neuron Projection Development Regulation Of Cell Migration Regulation Of GTPase Activity Positive Regulation Of Translation Positive Regulation Of Axonogenesis Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance Excitatory Synapse Assembly Regulation Of Neuron Migration	Actin Filament Organization Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Neuron Remodeling Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization
Pathways			SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse RND1 GTPase cycle
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576 29875488) Cutaneous malignant melanoma ( 32341527) Cutaneous melanoma or hair colour ( 32341527) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte counts ( 32888494) Nevus count or cutaneous melanoma ( 32341527) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sensorimotor dexterity ( 31596458) Systolic blood pressure ( 30224653)	Bipolar disorder ( 21926972)
Interacting Genes		7 interacting genes: ARHGEF11 ARHGEF12 CENPU HMOX2 PFDN1 PTN RND1	25 interacting genes: ARFIP2 ARHGAP5 CCNI COPS2 CREB3L2 EEF1A1 FRS2 FRS3 GPX8 GRB7 ID3 KRT6A MYH7 MYOM3 MYZAP NEDD1 PAIP1 PDE6D PLXNA1 PLXNB1 PLXNB2 RAI14 SHMT2 UBXN11 ZNF212
Entrez ID		23654	27289
HPRD ID		05050	12357
Ensembl ID		ENSG00000196576	ENSG00000172602
Uniprot IDs		O15031	Q92730
PDB IDs		4E71	2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?
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